What is the cause of a knot behind the ear?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for a Knot Behind the Ear

Single Most Likely Diagnosis

  • Lymphadenopathy: This is the most common cause of a knot or swelling behind the ear, often due to a viral or bacterial infection, or as a reaction to an infection elsewhere in the body. The lymph nodes behind the ear can become enlarged and feel like a knot.

Other Likely Diagnoses

  • Mastoiditis: An infection of the mastoid bone, which is located behind the ear. It can cause swelling, pain, and a knot-like sensation in the area.
  • Abscess or Cyst: A collection of pus or a fluid-filled sac behind the ear can feel like a knot. These can be caused by infections, blocked glands, or other skin conditions.
  • Trauma: A blow to the head or ear can cause a hematoma (collection of blood) or a swelling that feels like a knot.

Do Not Miss Diagnoses

  • Meningitis: Although less common, a knot behind the ear could be a sign of meningitis, especially if accompanied by symptoms like fever, headache, and stiff neck. Meningitis is a serious and potentially life-threatening condition that requires immediate medical attention.
  • Cancer: Rarely, a knot behind the ear could be a sign of a cancerous tumor, such as a lymphoma or a parotid gland tumor. While unlikely, missing a diagnosis of cancer could have severe consequences.

Rare Diagnoses

  • Branchial Cleft Cyst: A congenital condition where a cyst forms behind the ear, which can feel like a knot. These are usually present from birth but may not become apparent until later in life.
  • Eagle Syndrome: A condition where the styloid process (a bone in the skull) is elongated and can cause a sensation of a knot or swelling behind the ear, along with pain and other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.