Is it normal to feel a slight breathing effort when first using a BiPAP‑Auto (AirCurve 10) at EPAP 4 cm H₂O and IPAP 8 cm H₂O in a 40‑year‑old man with Upper Airway Resistance Syndrome using a nasal‑pillow mask?

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Last updated: February 18, 2026View editorial policy

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Initial BiPAP Discomfort at Low Pressures is Normal and Expected

Yes, feeling that you need to concentrate on breathing and experiencing slight inhalation effort during your first 30 minutes on BiPAP at EPAP 4/IPAP 8 cm H₂O is completely normal and expected—this is the standard acclimation period that all new PAP users experience. 1

Why This Happens

Your current settings (EPAP 4 cm H₂O and IPAP 8 cm H₂O) represent the minimum recommended starting pressures for BiPAP therapy in adults. 1 These are deliberately set low to allow gradual acclimation, not to provide your final therapeutic pressure. The pressure support of only 4 cm H₂O (IPAP minus EPAP) is the absolute minimum differential, which explains why inhalation doesn't feel fully assisted yet. 1, 2

The Acclimation Process

  • Pre-titration acclimatization is a standard requirement before any PAP therapy begins—patients should wear the interface with pressure on while awake to adjust to the sensation before attempting sleep. 1
  • The conscious awareness of breathing and mild effort you're experiencing represents normal adjustment to positive pressure ventilation, not device malfunction. 1
  • Your brain is accustomed to breathing against zero resistance; now you're breathing against 4 cm H₂O of expiratory pressure and receiving 8 cm H₂O during inspiration, which requires neurological adaptation. 1

What to Expect Next

During Attended Titration (If Scheduled)

  • Pressures will be increased gradually—by at least 1 cm H₂O every 5 minutes minimum—until your respiratory events (apneas, hypopneas, RERAs, snoring) are eliminated. 1, 3
  • For Upper Airway Resistance Syndrome specifically, the goal is to eliminate respiratory effort-related arousals and snoring, which may require higher pressures than your current settings. 1
  • The maximum IPAP can go up to 30 cm H₂O if needed, with pressure support potentially reaching 20 cm H₂O. 1, 2

Common Pitfall to Avoid

  • Do not abandon therapy during this initial discomfort phase. The first 30 minutes to several hours represent the learning curve that precedes therapeutic benefit. 1
  • If you're using a nasal-pillow mask and experiencing mouth breathing, this will worsen the sensation of effort—a chinstrap or switching to a full-face mask may be needed. 1

Immediate Steps to Improve Comfort

  • Continue wearing the device while awake for at least another 30-60 minutes to extend acclimation before attempting sleep. 1
  • Focus on relaxing and allowing the machine to do the work rather than fighting against it—the BiPAP will deliver higher pressure during inhalation automatically. 1
  • Ensure your mask fit is optimal with minimal leak, as excessive leak forces you to work harder to breathe and triggers pressure compensation. 1
  • Request heated humidification if you develop nasal dryness or congestion, as this significantly improves tolerance. 1, 3

When to Seek Adjustment

  • If after 2-3 hours of acclimation you still cannot tolerate the current pressures, contact your sleep medicine provider to discuss starting at a slightly higher IPAP (e.g., 10 cm H₂O) to provide more noticeable inspiratory assistance. 3
  • If you experience persistent air hunger, gasping, or inability to exhale comfortably, these may indicate the need for immediate pressure adjustment rather than simple acclimation. 1

The sensation you're describing is the expected initial response to BiPAP therapy and should diminish significantly within the first few hours of use as your respiratory control centers adapt to positive pressure ventilation. 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

BiPAP Setup and Titration for OSA with OHS

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

CPAP Pressure Settings for OSA Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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