What is the diagnosis for thickening of the peroneus brevis tendon at its insertion at the base of the fifth metatarsal?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Thickening of Peroneus Brevis Tendon at Insertion at Base of Fifth Metatarsal

  • Single Most Likely Diagnosis
    • Peroneal tendinosis or tendinitis: This condition is the most likely due to the location and nature of the complaint. The peroneus brevis tendon is prone to inflammation and degeneration, especially at its insertion point, leading to thickening and potential pain.
  • Other Likely Diagnoses
    • Peroneus brevis tendon rupture: A rupture could present with thickening of the tendon due to the body's attempt to repair the injury, and it often occurs at the insertion point.
    • Peroneal tenosynovitis: Inflammation of the tendon sheath surrounding the peroneus brevis tendon can cause swelling and thickening in the area.
    • Bony spur or fracture at the base of the fifth metatarsal: A bony abnormality could irritate the tendon, leading to thickening.
  • Do Not Miss Diagnoses
    • Jones fracture: A stress fracture of the fifth metatarsal bone, which could be associated with peroneus brevis tendon pathology due to its proximity and potential for shared risk factors.
    • Erythromelalgia: A rare condition characterized by burning pain, heat, and redness in the hands and feet, which could potentially cause or be associated with tendon thickening due to chronic inflammation.
  • Rare Diagnoses
    • Tumors (e.g., giant cell tumor, lipoma): Although rare, tumors can cause thickening of the tendon or surrounding tissues.
    • Inflammatory arthropathies (e.g., rheumatoid arthritis, psoriatic arthritis): These conditions can cause widespread inflammation, including in the tendons, leading to thickening.
    • Infectious tenosynovitis: An infection within the tendon sheath, which is rare but serious and requires prompt treatment.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.