When can the dose of Vyvanse (lisdexamfetamine) be increased?

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Last updated: April 23, 2025View editorial policy

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From the Research

Vyvanse dosage increases should be considered after consulting with a healthcare provider, typically after 1-2 weeks on your current dose if symptoms of ADHD or binge eating disorder aren't adequately controlled, as supported by the most recent study 1. The standard starting dose is 30mg once daily, with potential increases in 10-20mg increments up to a maximum of 70mg daily. Key factors to consider when evaluating the need for a dosage increase include:

  • Symptom control: If symptoms of ADHD or binge eating disorder are not adequately controlled, a dosage increase may be necessary.
  • Side effects: Common side effects of Vyvanse include insomnia, decreased appetite, and increased heart rate, which should be carefully monitored and managed.
  • Overall response: The healthcare provider will evaluate the patient's overall response to the medication, including any improvements in focus, impulse control, and overall quality of life. Some important points to note when considering a dosage increase:
  • Never increase Vyvanse on your own, as it is a controlled substance with potential for serious side effects if not properly managed.
  • Dosage changes should account for the patient's medical history, other medications, and individual metabolism.
  • The medication works by being converted to dextroamphetamine in the body, which increases dopamine and norepinephrine levels in the brain to improve focus and impulse control, so proper dosing is essential for both safety and effectiveness, as noted in studies 2, 3, 4, 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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