What is the most likely diagnosis for a 79-year-old female with acute onset of non-radiating middle abdominal pain and vomiting, unable to keep down liquids or oral Zofran (ondansetron)?

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Differential Diagnosis for 79 YOF with Middle Abdominal Pain and Vomiting

  • Single most likely diagnosis:
    • Small bowel obstruction: This is a common cause of middle abdominal pain and vomiting, especially in elderly patients. The inability to keep down liquids or oral medication suggests a possible obstruction.
  • Other Likely diagnoses:
    • Gastroenteritis: Viral or bacterial infection can cause abdominal pain, vomiting, and dehydration, which may be severe in elderly patients.
    • Mesenteric ischemia: Reduced blood flow to the intestines can cause abdominal pain, vomiting, and may lead to bowel infarction if not promptly treated.
    • Diverticulitis: Inflammation of the diverticula in the colon can cause abdominal pain, vomiting, and may lead to complications such as abscess or perforation.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Appendicitis: Although less common in elderly patients, appendicitis can present with atypical symptoms and may lead to perforation and peritonitis if not promptly treated.
    • Perforated viscus: A hole in the stomach or intestine can cause severe abdominal pain, vomiting, and may lead to peritonitis and sepsis if not promptly treated.
    • Pancreatitis: Inflammation of the pancreas can cause severe abdominal pain, vomiting, and may lead to complications such as necrotizing pancreatitis or pseudocyst formation.
  • Rare diagnoses:
    • Intussusception: A condition where a part of the intestine telescopes into another part, causing obstruction and potentially leading to bowel infarction.
    • Volvolus: A twisting of the intestine that can cause obstruction and potentially lead to bowel infarction.
    • Abdominal aortic aneurysm: A rupture of the aortic aneurysm can cause severe abdominal pain, vomiting, and may lead to shock and death if not promptly treated.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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