Brand Name of Tiotropium
The brand name of tiotropium is Spiriva, manufactured by Boehringer Ingelheim. 1, 2, 3
Available Formulations
Tiotropium is marketed under the Spiriva brand in two distinct delivery systems:
- Spiriva HandiHaler: Delivers tiotropium as a dry powder at 18 μg dose 1, 3, 4
- Spiriva Respimat: Delivers tiotropium as a soft mist inhalation spray at 5 μg dose (reduced dosage due to improved lung deposition) 1, 2, 5, 4
Combination Product
- Stiolto Respimat: A combination product containing tiotropium bromide and olodaterol (2.5 mcg/2.5 mcg per actuation) also marketed by Boehringer Ingelheim 2
Generic Availability
While Spiriva is the established brand name, generic versions of tiotropium bromide exist in some markets (such as Tiova), though until recently there was no long-acting generic alternative available in the United States. 1, 6
The HandiHaler device has been the traditional delivery system used in the majority of clinical studies establishing tiotropium's efficacy, while the Respimat system represents a newer delivery technology that allows for reduced dosing while maintaining equivalent therapeutic effects. 1, 5, 4