When is skin stapling preferred over suturing for surgical wound closure?

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Last updated: February 19, 2026View editorial policy

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Skin Closure Method Selection

Primary Recommendation

Sutures should be your first-line method for most surgical wound closures, as they provide superior wound integrity and significantly lower dehiscence rates compared to both staples and tissue adhesives. 1

Evidence-Based Decision Algorithm

For Most Surgical Wounds: Use Continuous Subcuticular Sutures

  • Continuous subcuticular sutures with slowly absorbable monofilament material (4-0 poliglecaprone or polyglactin) are the optimal choice, reducing superficial wound dehiscence by 92% (RR 0.08; 95% CI 0.02-0.35) compared to interrupted techniques. 1

  • These sutures retain 50-75% tensile strength after 1 week and eliminate the need for painful removal at 7-9 days postoperatively. 1

  • Maintain a suture-to-wound length ratio of at least 4:1 using the "small bite" technique (5mm from wound edge, 5mm between stitches) to minimize incisional hernia risk. 1

When Staples May Be Considered

Staples offer only one clinical advantage—speed of closure (22.5 cm/minute vs 4.2 cm/minute for sutures)—but this comes at the cost of increased complications. 2

  • Staples cause significantly higher rates of inflammation, discomfort on removal, and spreading of healing scars compared to sutures. 3

  • In cardiovascular surgery specifically, three out of five randomized trials found lower complication rates with sutures, and two studies demonstrated superior cosmesis with sutures. 4

  • The time savings with staples (average 3 minutes per wound) does not justify the increased patient morbidity and inferior cosmetic outcomes. 2, 3

Tissue Adhesives: Avoid for Most Closures

  • Tissue adhesives carry a 3.35-fold higher risk of wound breakdown compared to sutures (RR 3.35; 95% CI 1.53-7.33), requiring treatment of 43 patients with sutures instead of glue to prevent one additional dehiscence. 1

  • Never use tissue adhesives alone in high-tension wounds, emergency laparotomy, abdominal wall closures, or any wound where mechanical forces are significant. 1

  • Adhesives may only be considered for very superficial lacerations <0.5 cm in low-tension areas where hemostasis is already achieved. 1

Special Circumstances Requiring Specific Suture Selection

Contaminated or Infection-Prone Wounds

  • Use triclosan-coated antimicrobial sutures (such as triclosan-coated Vicryl), which reduce surgical site infection risk by 28% (OR 0.72; 95% CI 0.59-0.88). 1

  • This is mandatory for abdominal and colorectal surgery where contamination risk is elevated. 1

High-Tension Wounds

  • High-tension wounds absolutely require sutures, as both tissue adhesives and staples fail where mechanical forces are significant. 1

  • Use slowly absorbable monofilament material with proper 4:1 ratio technique. 1

Critical Pitfalls to Avoid

  • Never use rapidly absorbable sutures for fascial closure, as they increase incisional hernia rates due to quick loss of tensile strength. 1

  • Avoid removing non-absorbable sutures or staples before 7-9 days, as premature removal causes dehiscence. 1

  • Don't pull continuous sutures too tightly, as this strangulates wound edges and causes ischemia. 1

  • Never include adipose tissue in abdominal sutures, as this significantly increases dehiscence, infection, and incisional hernia risk. 1

Practical Implementation

Optimal Suture Technique

  • Place stitches in the subcuticular layer using continuous technique with slowly absorbable monofilament. 1

  • Include only the aponeurosis (not fat or muscle) to reduce complication risk. 1

  • Ensure adequate wound support by maintaining the 4:1 suture-to-wound length ratio throughout closure. 1

Post-Closure Monitoring

  • Monitor for signs of infection (increasing pain, redness, swelling, discharge) regardless of closure method chosen. 1

  • Watch specifically for wound dehiscence in the first 7-10 days postoperatively. 1

  • Pain disproportionate to injury severity may suggest deeper complications requiring immediate evaluation. 5

References

Guideline

Wound Closure Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Staples for wound closure: a controlled trial.

Annals of the Royal College of Surgeons of England, 1985

Research

Skin closure using staples and nylon sutures: a comparison of results.

Annals of the Royal College of Surgeons of England, 1987

Research

Staples or sutures for chest and leg wounds following cardiovascular surgery.

Interactive cardiovascular and thoracic surgery, 2007

Guideline

Skin Glue for Wound Closure

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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