What is the most appropriate next step in evaluating an adult with right neck, shoulder, and leg pain?

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Evaluation of Right Neck, Shoulder, and Leg Pain

Initial Diagnostic Approach

Begin with plain radiographs of the cervical spine and right shoulder as the first-line imaging to exclude fractures, dislocations, degenerative changes, and structural abnormalities. 1, 2, 3

The combination of neck, shoulder, and leg pain on the same side suggests either:

  • Cervical radiculopathy with referred pain patterns (most likely given the distribution) 1, 4
  • Concurrent cervical spine and shoulder pathology requiring separate evaluation 5
  • Cervical myelopathy if leg symptoms suggest upper motor neuron involvement 6

Critical History Elements to Obtain

Document these specific red-flag symptoms immediately: 1, 2

  • Progressive neurological deficits (weakness, numbness, gait disturbance)
  • Fever or constitutional symptoms suggesting infection
  • Significant trauma history
  • Unexplained weight loss or history of malignancy
  • Bowel/bladder dysfunction

Characterize the pain distribution precisely: 1, 3, 5

  • Neck pain radiating down the arm into specific dermatomal patterns indicates cervical radiculopathy 1, 4
  • Anterior shoulder pain suggests rotator cuff or biceps pathology 3
  • Leg pain with neck/shoulder involvement raises concern for myelopathy or multilevel radiculopathy 6

Determine the temporal pattern: 1, 3

  • Acute onset (<2 weeks) versus chronic (>6 months)
  • Mechanism of injury if traumatic
  • Activities that aggravate symptoms (overhead activities suggest shoulder pathology; neck rotation/extension suggest cervical spine) 3, 5

Physical Examination Priorities

Perform these specific maneuvers to differentiate cervical from shoulder pathology: 1, 3, 5

For cervical radiculopathy: 1, 4

  • Spurling test (neck extension with rotation and axial compression toward symptomatic side)
  • Upper limb tension tests
  • Dermatomal sensory examination
  • Myotomal strength testing (C5-T1)
  • Deep tendon reflexes (biceps C5-C6, triceps C7, brachioradialis C6)

For shoulder pathology: 3

  • Hawkins test (92% sensitive for impingement)
  • Neer test (88% sensitive for impingement)
  • Empty can test for supraspinatus
  • External rotation strength testing
  • Passive versus active range of motion (preserved passive with limited active suggests rotator cuff tear)

For myelopathy (critical if leg symptoms present): 6, 7

  • Gait assessment
  • Hoffmann sign
  • Hyperreflexia in lower extremities
  • Clonus
  • Babinski sign
  • Fine motor coordination (button test, coin test)

Imaging Algorithm

Step 1: Initial Radiographs (First-Line)

Obtain these views immediately: 1, 2, 3

  • Cervical spine: AP, lateral, oblique views 1
  • Right shoulder: AP (internal and external rotation), axillary or scapular-Y views 3
  • Chest radiograph if intercostal pain component present 2

Step 2: Advanced Imaging Based on Initial Findings

If radiographs are normal or equivocal AND red flags are absent: 1

  • Trial of conservative management for 4-6 weeks is appropriate
  • Reserve MRI for persistent symptoms despite conservative care

If radiographs are normal BUT red flags are present or neurological deficits exist: 1, 2

  • MRI cervical spine without contrast is the next appropriate study 1
  • MRI is the most sensitive modality for disc herniations, osteophytes, spinal cord compression, and nerve root impingement 1, 4, 7

If shoulder radiographs are normal but clinical examination strongly suggests rotator cuff pathology: 3

  • MRI shoulder without contrast for patients >35 years with suspected rotator cuff tear 1, 3
  • Ultrasound is equivalent to MRI for rotator cuff evaluation when performed by experienced operators (85% sensitivity, 90% specificity) 3

If myelopathy is suspected (leg involvement with upper motor neuron signs): 6, 7

  • MRI cervical spine without contrast is mandatory to assess for spinal cord compression 6
  • This is a surgical urgency if progressive deficits are present 6, 7

Laboratory Testing

Order these tests if infection or inflammatory process is suspected: 2

  • Complete blood count
  • Erythrocyte sedimentation rate
  • C-reactive protein

Consider cardiac workup if atypical pain characteristics or cardiovascular risk factors: 2

  • Troponin
  • ECG

Conservative Management (If No Red Flags)

For cervical radiculopathy: 1, 4, 7

  • 75-90% of patients improve with conservative care 1
  • NSAIDs (ibuprofen 400-600 mg every 8 hours or naproxen 500 mg every 12 hours) 2
  • Pregabalin 150 mg twice daily for neuropathic pain (if radicular symptoms confirmed) 2
  • Physical therapy focusing on gentle range of motion and strengthening 4, 7
  • Avoid aggressive manipulation or traction initially 7

For shoulder impingement/rotator cuff tendinopathy: 3

  • Complete rest from aggravating activities 3
  • NSAIDs for pain control 2, 3
  • Physical therapy with focus on external rotation and scapular stabilization 3
  • Avoid overhead pulley exercises (worsen rotator cuff pathology) 3
  • Consider subacromial corticosteroid injection if conservative measures fail after 4-6 weeks 3

Critical Pitfalls to Avoid

Do not assume "muscle tension" without excluding structural cervical pathology, especially with red flags present. 2

Do not delay MRI if progressive neurological deficits are present—this may represent myelopathy requiring urgent surgical decompression. 6, 7

Do not confuse cervical radiculopathy with isolated shoulder pathology—cervical spondylosis commonly causes radiating arm pain that mimics rotator cuff disease. 5

Do not overlook multilevel pathology—concurrent cervical and shoulder disease is common, particularly in patients >40 years. 5

Urgent Referral Indications

Immediate neurosurgical or orthopedic spine consultation if: 6, 7

  • Progressive myelopathy (gait disturbance, hyperreflexia, upper motor neuron signs)
  • Acute spinal cord compression on imaging
  • Progressive motor weakness despite conservative care

Orthopedic shoulder referral if: 3

  • Complete rotator cuff tear on imaging in active patient
  • Failure of 3-6 months conservative management for impingement
  • Acute traumatic shoulder dislocation with suspected labral injury

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnostic Evaluation and Treatment of Right Intercostal Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Shoulder Pain Evaluation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Cervical radiculopathy.

The Medical clinics of North America, 2014

Research

Cervical spondylotic myelopathy.

The neurologist, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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