From the Research
Low testosterone in a 39-year-old female should be addressed by consulting a healthcare provider for blood tests to confirm low testosterone levels, and treatment typically involves addressing underlying causes rather than direct testosterone supplementation, with lifestyle modifications and potential off-label use of low-dose testosterone cream or gel (0.5-2% concentration) applied daily to the skin. The symptoms of low testosterone in women can include fatigue, decreased libido, muscle weakness, and mood changes 1. If these symptoms are present, it is essential to consult with a healthcare provider for proper diagnosis and treatment. The healthcare provider will likely order blood tests to confirm low testosterone levels and rule out other potential causes of symptoms. Some key points to consider in the management of low testosterone in women include:
- Lifestyle modifications to support hormone balance, such as regular exercise, adequate sleep (7-8 hours nightly), stress management, maintaining a healthy weight, and a balanced diet rich in zinc, vitamin D, and healthy fats 1
- Certain medical conditions, like polycystic ovary syndrome, adrenal disorders, or pituitary issues, can affect testosterone levels and require specific treatment 2
- Birth control pills and some medications can also lower testosterone, so the doctor might adjust these if appropriate 3
- Regular monitoring is essential if treatment is initiated to prevent side effects like acne, hair growth, or voice deepening 4 It is also important to note that testosterone replacement is not FDA-approved for women and is used off-label, usually as a low-dose cream or gel (0.5-2% concentration) applied daily to the skin 3. The most recent study on androgens during the reproductive years found that all C19 androgens declined with age before menopause, highlighting the need for age-specific reference ranges for the interpretation of androgen levels in premenopausal women 1.