Which medications are family‑practice nurse practitioners (FNP) prohibited from prescribing in Texas?

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Last updated: February 19, 2026View editorial policy

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Texas FNP Prescribing Restrictions

Family nurse practitioners in Texas operate under restrictive prescriptive authority regulations that require physician collaboration and delegation, but there are no specific medications categorically prohibited from FNP prescribing based solely on drug class—rather, prescribing scope is determined by the supervising physician's delegation and the collaborative practice agreement.

Regulatory Framework in Texas

Texas maintains restrictive NP practice regulations that do not grant full practice authority (FPA), meaning FNPs cannot prescribe independently without physician oversight. 1

  • Texas law requires FNPs to practice under a written prescriptive authority agreement with a supervising physician, who determines which medications the FNP may prescribe 2
  • The supervising physician's scope of practice and willingness to delegate determines what medications are accessible to the FNP, not a state-mandated prohibited drug list 2
  • This creates significant variability in prescribing capacity between individual FNPs based on their collaborative agreements 1

Controlled Substances Considerations

Schedule I controlled substances (such as heroin) cannot be prescribed by any healthcare provider, including FNPs, as these substances have no accepted medical use. 3

  • Schedule II-V controlled substances may be prescribed by FNPs in Texas if specifically delegated by the supervising physician and included in the prescriptive authority agreement 2
  • Many FNPs face practical restrictions on prescribing higher-schedule controlled substances (particularly Schedule II opioids) even when legally permitted, due to physician reluctance to delegate this authority 4, 5
  • FNPs with independent prescriptive authority in other states show over 20 times higher rates of opioid prescribing compared to those in prescription-restricted states like Texas, demonstrating how regulatory frameworks limit prescribing patterns 4

Medication Classes Requiring Special Consideration

Certain high-risk medications may be restricted in FNP practice agreements despite no absolute state prohibition:

  • Isotretinoin requires iPLEDGE program enrollment and extensive monitoring for teratogenicity, which many supervising physicians may not delegate to FNPs 6
  • Buprenorphine for opioid use disorder requires a federal waiver (DATA 2000 waiver, now modified), and while FNPs can obtain this waiver, only 80.3% of waivered NPs/PAs actually prescribe it 5
  • Lithium requires therapeutic drug monitoring and renal function assessment, though no specific prescribing restrictions exist for FNPs with appropriate delegation 7, 8

Common Practical Restrictions

The following medication categories are frequently excluded from FNP prescriptive authority agreements in restrictive states, though not explicitly prohibited by Texas law:

  • High-dose or long-term opioid prescriptions (≥100 MME/day or >90 days duration) are often restricted by supervising physicians 4
  • Chemotherapeutic agents and other oncology medications typically require specialist oversight 6
  • Complex psychiatric medications including MAOIs and certain antipsychotics may be restricted depending on the FNP's specialty training 6, 8
  • Medications requiring specialized monitoring programs (like clozapine registries) are often excluded from FNP agreements 6

Key Clinical Pitfall

The critical issue in Texas is not a list of prohibited medications, but rather the variability and restrictions imposed by individual collaborative practice agreements. FNPs must carefully review their specific prescriptive authority agreement to understand their scope, as this varies dramatically between practice settings and supervising physicians 2, 1. Evidence demonstrates that restrictive state regulations like those in Texas do not improve patient safety outcomes but do significantly limit healthcare access 9, 1.

References

Research

A case for the health welfare of Texans-A nurse practitioner state regulation policy analysis.

Journal of the American Association of Nurse Practitioners, 2024

Research

Legal parameters of drug prescriptions by NPs.

The Nurse practitioner, 1985

Guideline

Schedule I Controlled Substances Classification

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Prescribing Practices of Nurse Practitioners and Physician Assistants Waivered to Prescribe Buprenorphine and the Barriers They Experience Prescribing Buprenorphine.

The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2020

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Contraception and Psychiatric Medication Interactions

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Antidepressant Selection and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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