What are the causes of ageusia (loss of taste)?

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Last updated: April 24, 2025View editorial policy

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Differential Diagnosis for Loss of Taste

  • Single most likely diagnosis
    • Viral upper respiratory infection: This is often the most common cause of loss of taste, as many viruses that cause upper respiratory infections can affect the taste buds and olfactory epithelium, leading to a temporary loss of taste.
  • Other Likely diagnoses
    • Medication side effects: Certain medications, such as antibiotics, antihistamines, and decongestants, can alter taste as a side effect.
    • Nutritional deficiencies: Deficiencies in vitamins like zinc, vitamin B12, or iron can lead to changes in taste perception.
    • Sinusitis or rhinitis: Chronic inflammation in the nasal passages can impair the sense of smell, which is closely linked to the sense of taste.
    • Aging: Older adults may experience a decline in their sense of taste due to natural aging processes.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Brain tumors or strokes: Although rare, tumors or strokes affecting the brain's taste centers can cause loss of taste. Early diagnosis is crucial for effective treatment.
    • Neurodegenerative diseases: Conditions like Alzheimer's disease or Parkinson's disease can lead to changes in taste perception.
    • Sjögren's syndrome: An autoimmune disorder that can cause dry mouth and loss of taste.
  • Rare diagnoses
    • Bell's palsy: A condition that causes facial paralysis and can affect the facial nerve, which is involved in taste.
    • Multiple sclerosis: A chronic autoimmune disease that can damage the nerves responsible for taste.
    • Head trauma: Severe head injuries can damage the nerves or brain areas responsible for taste.
    • Certain infections: Such as meningitis or encephalitis, which can affect the brain's taste centers.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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