Normal CBC Differential - No Further Evaluation Needed
These differential values (neutrophils 63%, lymphocytes 27%, monocytes 8%, eosinophils 2%) fall within normal reference ranges for a healthy adult and do not require further evaluation. 1, 2
Reference Ranges for Peripheral Blood Differential
Your values align with established normal ranges:
- Neutrophils 63%: Normal range is 45-75% 3
- Lymphocytes 27%: Normal range is 16-46% 3
- Monocytes 8%: Normal range is 4-11% 3
- Eosinophils 2%: Normal range is 0-5% (typically <3%) 3
All four cell populations are well within their respective normal limits. 3, 1
Clinical Interpretation
No pathologic findings are present. The differential shows:
- A physiologic neutrophil predominance, which is expected in healthy adults 1
- Normal lymphocyte percentage without lymphocytosis or lymphopenia 3, 1
- Normal monocyte percentage 3
- Normal eosinophil percentage, ruling out eosinophilia (which would require >5% or absolute count considerations) 3
When to Investigate Further
Further evaluation would only be warranted if:
- Total WBC count is elevated (>11,000 cells/mm³) with absolute neutrophil count >6,700 cells/mm³, suggesting possible bacterial infection even without fever 1
- Clinical symptoms are present such as fever, signs of infection, unexplained fatigue, or lymphadenopathy 3, 1
- Band forms (immature neutrophils) are elevated (>5% or absolute band count >1,500/mm³), which would indicate a "left shift" suggestive of acute bacterial infection 1, 2
- Absolute cell counts are abnormal despite normal percentages (requires knowing total WBC count) 1
Common Pitfall to Avoid
Do not confuse these peripheral blood differential ranges with bronchoalveolar lavage (BAL) differential ranges, which have entirely different normal values (BAL: 85-95% macrophages, 4-15% lymphocytes, <3% neutrophils, <1% eosinophils). 3, 2, 4 The question refers to peripheral blood, where your values are completely normal.