Does Entyvio (Vedolizumab) cause burning sensation in the feet?

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Last updated: April 24, 2025View editorial policy

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From the Research

Entyvio (vedolizumab) is not typically associated with burning sensations in the feet as a common side effect. This medication, which is used to treat ulcerative colitis and Crohn's disease, works by blocking certain inflammatory pathways in the gut specifically, rather than affecting the whole body. The most common side effects of Entyvio include headache, joint pain, nausea, fever, upper respiratory tract infections, fatigue, rash, and sinus infections. Burning sensations in the feet could potentially indicate peripheral neuropathy, which is not a known direct side effect of Entyvio.

If you're experiencing burning feet while taking Entyvio, it's essential to consult your healthcare provider promptly as this symptom might be related to another condition, a rare reaction, or possibly an interaction with other medications. Your doctor can evaluate whether the burning sensation is connected to your medication regimen or if it requires separate investigation and treatment. The provided evidence does not directly link Entyvio to burning sensations in the feet, with studies focusing on natalizumab, a different medication, and its effects on multiple sclerosis and epilepsy 1, 2, 3, 4, 5.

Key points to consider:

  • Entyvio's mechanism of action is specific to the gut, reducing the likelihood of it causing burning sensations in the feet.
  • Common side effects of Entyvio do not include burning sensations in the feet.
  • Burning sensations in the feet could be indicative of another condition, such as peripheral neuropathy, which requires medical evaluation.
  • Consultation with a healthcare provider is necessary to determine the cause of burning feet and appropriate treatment.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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