Can metoprolol (Lopressor) tartrate cause xerosis (dry skin)?

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Last updated: April 24, 2025View editorial policy

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From the Research

Metoprolol tartrate can cause dry skin as a side effect, though it's not among the most common reactions. Metoprolol is a beta-blocker medication primarily used to treat high blood pressure, angina, and heart failure, typically prescribed at doses ranging from 25-100 mg twice daily. The dry skin occurs because beta-blockers can affect blood flow to the skin and potentially alter sweat gland activity. If you experience dry skin while taking metoprolol, using a gentle, fragrance-free moisturizer regularly may help manage this symptom. It's essential to note that the most recent and highest quality study 1 does not specifically mention dry skin as a side effect, but it does discuss the safety and efficacy of metoprolol in combination with other medications. However, an older study 2 mentions that metoprolol can cause psoriasiform and/or eczematous skin lesions in some patients.

Key Points to Consider

  • Metoprolol is generally well-tolerated, but it can cause skin-related side effects in some patients 2.
  • The medication can affect blood flow to the skin and potentially alter sweat gland activity, leading to dry skin.
  • If you experience dry skin while taking metoprolol, using a gentle, fragrance-free moisturizer regularly may help manage this symptom.
  • It's crucial not to stop taking metoprolol without consulting your healthcare provider, as suddenly discontinuing this medication can lead to serious cardiac issues.
  • If the dry skin becomes severe, bothersome, or is accompanied by other side effects like rash or itching, contact your doctor, as they might adjust your dosage or recommend an alternative medication that better suits your body's response.

Management and Prevention

  • Regularly using a gentle, fragrance-free moisturizer may help manage dry skin symptoms.
  • Avoiding harsh soaps and cleansers can also help prevent dry skin.
  • If you experience any skin-related side effects, consult your healthcare provider for guidance on managing these symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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