Is a 12‑hour urine output of 1200 mL (≈100 mL/hr) normal for a 29‑year‑old male weighing 42 kg, or does it indicate polyuria?

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Urine Output Assessment for 29-Year-Old Male, 42 kg

This patient's 12-hour urine output of 1200 mL (100 mL/hour or 2400 mL/24 hours) is within normal limits and does not indicate polyuria. 1, 2

Normal Urine Output Parameters

  • Normal adult urine output ranges from approximately 800–2000 mL per 24 hours, with guidelines suggesting a target of approximately 1 liter per 24 hours for healthy individuals 2
  • Polyuria is defined as urine output exceeding 3 liters per 24 hours in adults, which is the standard diagnostic threshold 1, 2, 3, 4
  • This patient's extrapolated 24-hour output of 2400 mL falls well below the 3000 mL polyuria threshold 1, 2

Weight-Based Considerations

  • For a 42 kg adult, the hourly output of 100 mL/hour translates to approximately 2.4 mL/kg/hour, which is substantially above the oliguria threshold of <0.5 mL/kg/hour 5
  • The patient's output demonstrates adequate kidney perfusion and function, as it exceeds oliguria thresholds by nearly 5-fold 5

Clinical Context

This output is reassuring and indicates normal renal function. The key distinction is:

  • Oliguria (<0.5 mL/kg/hour for ≥6 hours, or <400 mL/day in a 70 kg adult) would be concerning 5
  • Anuria (<100 mL per 24 hours) would be critical 6, 5
  • Polyuria (>3000 mL per 24 hours) would warrant investigation 1, 2, 3

Important Caveats

  • A single 12-hour measurement should not be used to definitively diagnose polyuria; the definition requires measurement over a full 24-hour period 1
  • If there are concerns about abnormal urine patterns, a 3-day frequency-volume chart documenting both number of voids and individual void volumes is the gold standard diagnostic tool to distinguish polyuria from other conditions like nocturnal polyuria or urinary frequency 1, 2
  • Do not confuse hourly urine output rates (which assess kidney function) with single void volumes (which reflect bladder capacity and voiding habits) 5

References

Guideline

Definition and Diagnosis of Polyuria

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Relationship Between Single Kidney and Polyuria/Nocturnal Polyuria

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Evaluation of Polyuria: The Roles of Solute Loading and Water Diuresis.

American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016

Guideline

Urine Output Thresholds

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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