What is the effect of Telmisartan (Angiotensin II receptor antagonist) on menstrual function?

From the Research

Effect of Telmisartan on Menstrual Function

There are no research papers to assist in answering this question, as the provided studies focus on the effects of telmisartan on hypertension, metabolic syndrome, and renal function, but do not mention its impact on menstrual function.

Key Findings on Telmisartan

• Telmisartan is an angiotensin II receptor antagonist used in the management of hypertension 1, 2, 3
• It has a partial PPARγ-agonistic effect and agonist activity on PPARα and PPARδ receptors, which may be beneficial in treating metabolic syndrome 1
• Telmisartan has been shown to be effective in reducing blood pressure and slowing the progression of renal dysfunction 2, 4
• It has a long-lasting antihypertensive effect and is well-tolerated in patients with mild to moderate hypertension 2, 5

Mechanism of Action

• Telmisartan binds to angiotensin II type 1 receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle 2, 3
• It has a slow dissociation rate from AT1 receptors, which contributes to its insurmountable antagonism 5