Can turmeric interact with Eliquis (apixaban)?

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Last updated: April 24, 2025View editorial policy

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From the Research

Turmeric can potentially interact with Eliquis (apixaban), and this combination should be approached with caution due to the risk of increased bleeding. The interaction between turmeric and Eliquis is concerning because turmeric contains curcumin, which has blood-thinning properties that may enhance the anticoagulant effect of Eliquis, potentially increasing the risk of bleeding 1. This is particularly relevant when considering the management of patients with atrial fibrillation, where the risk of bleeding is already a significant concern, as highlighted in studies such as the ARISTOTLE trial 2. The risk of major bleeding is a critical consideration in the management of anticoagulation therapy, and any potential interactions that could increase this risk, such as the use of turmeric supplements, should be carefully evaluated 3, 4. Given the potential for increased bleeding risk, it is essential for patients taking Eliquis to consult with their healthcare provider before using turmeric supplements, as they may need to monitor for signs of unusual bleeding or adjust their medication regimen accordingly 5. Small amounts of turmeric used in cooking are generally considered less risky than concentrated supplements, but medical guidance is still advisable to minimize the risk of adverse interactions. Key considerations for healthcare providers include:

  • Monitoring patients for signs of bleeding, such as nosebleeds or bruising
  • Adjusting medication regimens as necessary to minimize the risk of bleeding
  • Educating patients on the potential risks of combining turmeric supplements with Eliquis
  • Encouraging patients to report any changes in their medication regimen or supplement use to their healthcare provider.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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