Causes of Costochondritis in Elderly Patients
Costochondritis in elderly patients is primarily caused by physical strain, repetitive movements, severe coughing, and age-related degenerative changes, though infectious causes must be excluded in this population given their higher risk of complications. 1
Primary Etiologic Factors
Mechanical and Inflammatory Causes
- Physical exertion and repetitive movements (such as lifting heavy objects) are the most common causes of costochondritis across all age groups 2, 1
- Severe or persistent coughing can trigger costochondral inflammation, particularly relevant in elderly patients with chronic respiratory conditions 2, 1
- Chest wall overuse from activities that stress the costochondral junctions leads to inflammation of the costochondral junctions of ribs or chondrosternal joints 1
Age-Related Considerations
- Degenerative changes in cartilage and joints become more prevalent with aging, potentially predisposing elderly patients to costochondritis, similar to other musculoskeletal conditions 3
- Osteoarthritis may coexist in elderly patients with costochondritis, as documented in emergency department studies where osteoarthritis was diagnosed in patients presenting with chest wall pain 4
Critical Differential: Infectious Costochondritis
High-Risk Features in Elderly Patients
- Infectious costochondritis must be considered in elderly patients, especially those with diabetes mellitus or immunocompromising conditions 2
- Infection typically spreads from postoperative wounds or adjacent foci, though hematogenous spread can occur 2
- Pseudomonas aeruginosa and other bacterial pathogens can cause infectious costochondritis with sternal osteomyelitis, presenting with persistent chest pain, swelling, and potential purulent drainage 2
Red Flags Requiring Immediate Investigation
- Persistent symptoms beyond 2-3 weeks without improvement suggest atypical or infectious costochondritis 5
- Purulent drainage, fever, or systemic signs mandate evaluation for infectious etiology 2
- Diabetes mellitus significantly increases risk of infectious complications 2
Associated Conditions in Elderly Patients
Comorbid Rheumatologic Disease
- Rheumatoid arthritis was identified in some patients presenting with costochondritis in emergency department cohorts 4
- Fibromyalgia coexists in a minority (8%) of costochondritis cases, though widespread pain is more common (42% of patients) 4
Important Clinical Context
- Women comprise 69% of costochondritis cases in emergency department settings 4
- The mean age in prospective studies was 50 years, with cases ranging from 26-75 years 6
- Spontaneous resolution occurs in most cases within one year, though 55% may have persistent chest pain at one-year follow-up 4
Diagnostic Pitfalls to Avoid
Cardiac Exclusion in Elderly Patients
- Patients older than 35 years must have electrocardiography to exclude coronary artery disease, which is present in 3-6% of adults with chest pain and chest wall tenderness 1
- The acute myocardial infarction rate was 6% in the costochondritis group versus 28% in control chest pain patients, but cardiac causes must still be systematically excluded 4
- Any patient with cardiopulmonary symptoms or cardiac risk factors requires chest radiography and further cardiac evaluation as clinically indicated 1