When should cardiopulmonary resuscitation be started in an unresponsive patient without normal breathing or a palpable pulse?

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When to Start CPR

Start CPR immediately when a patient is unresponsive with no normal breathing (or only gasping) and no definite pulse felt within 10 seconds. 1, 2

Recognition Algorithm for Healthcare Providers

Simultaneous assessment (within 10 seconds maximum): 3, 1

  • Check responsiveness by shouting and tapping the victim 1, 2
  • Look for absent or abnormal breathing (only gasping counts as absent breathing) 3, 1
  • Palpate for a pulse simultaneously—do not spend more than 10 seconds on this 3, 1

If uncertain about pulse presence after 10 seconds, start CPR immediately rather than continuing to search for a pulse, as delays worsen outcomes and pulse checks are unreliable. 3, 1

Decision Points Based on Assessment

Scenario 1: No pulse (or uncertain) + No normal breathing

Action: Start CPR immediately with chest compressions first 3, 1, 2

Scenario 2: Definite pulse present + No normal breathing

Action: Provide rescue breathing only (1 breath every 6 seconds in adults, 1 breath every 2-3 seconds in children), and recheck pulse every 2 minutes. 3, 2

Scenario 3: Pediatric-specific threshold

Action: Start CPR if heart rate <60 bpm AND signs of poor perfusion are present (mottled/pale skin, weak pulses, altered mental status). 4, 3

Critical Timing Considerations

Do not delay CPR beyond 10 seconds for pulse assessment. Healthcare providers have only 78% accuracy in detecting pulses, and prolonged pulse checks (averaging 20 seconds in practice) significantly delay life-saving compressions. 3, 5

Early CPR initiation (within 1.9 minutes) improves survival two-fold to three-fold compared to delayed CPR (5.7 minutes). The benefit exists within a narrow 4-6 minute window from collapse. 6

For Lay Rescuers (Simplified Criteria)

Lay rescuers should begin CPR for any victim who is unresponsive and not breathing normally—do not check for a pulse. 3 Pulse checks are unreliable for untrained rescuers (only 47% accuracy at 5 seconds), so the presence of unresponsiveness plus absent/abnormal breathing is sufficient. 3

Common Pitfalls to Avoid

  • Do not perform prolonged pulse checks beyond 10 seconds—if uncertain, start compressions. 1, 2
  • Do not mistake agonal gasping for normal breathing—gasping indicates cardiac arrest and requires immediate CPR. 3, 1
  • Do not delay compressions to obtain history or establish IV access—chest compressions are the immediate priority. 1
  • In pediatric bradycardia, do not start CPR if perfusion is adequate (heart rate <60 but good color, strong pulses)—provide rescue breathing only and reassess frequently. 4

References

Guideline

Cardiac Arrest Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Adult Cardiopulmonary Resuscitation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Initiation of CPR in Bradycardic Infants with Poor Perfusion

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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