From the Research
Fluconazole is not typically used as a topical treatment for candida infections, and instead, medications like clotrimazole, miconazole, or nystatin are preferred for topical application. For topical treatment of candidiasis, the following options are recommended:
- Clotrimazole 1% cream applied twice daily for 1-2 weeks
- Miconazole 2% cream applied twice daily for 1-2 weeks
- Nystatin cream applied 2-3 times daily for 1-2 weeks These topical antifungals work by disrupting the fungal cell membrane, preventing growth and reproduction of the candida organism 1. Fluconazole is an oral antifungal medication, usually prescribed at 150 mg as a single dose for uncomplicated vaginal candidiasis, or 100-200 mg daily for 7-14 days for other candida infections. If the infection is severe or doesn't respond to topical treatment, then oral fluconazole might be recommended by a healthcare provider as a systemic approach 2. It's essential to note that fluconazole is not suitable for topical use, and its effectiveness and safety profile are well-established for oral administration 3, 4.