From the Research
Angular cheilitis is best treated with a combination of 1% isoconazole nitrate (ISN) and 0.1% diflucortolone valerate (DFV) ointment applied to the affected corners of the mouth, as this combination has been found to be the most consistent treatment due to its broad spectrum of activity against dermatophytes and bacteria, and its anti-inflammatory properties 1.
Treatment Approach
The treatment of angular cheilitis should focus on addressing the underlying causes, which may include moisture accumulation, yeast or bacterial overgrowth, vitamin deficiencies, poorly fitting dentures, drooling during sleep, or immune suppression.
- Keep the affected areas clean and dry, and avoid licking the corners of your mouth.
- Apply petroleum jelly as a barrier after treatment to prevent further irritation.
- For severe or persistent cases, oral antifungals may be necessary, but this should be determined on a case-by-case basis.
Underlying Causes
It is essential to identify and address the underlying causes of angular cheilitis to prevent recurrence.
- Vitamin deficiencies, such as B vitamins, iron, or zinc, should be corrected through dietary changes or supplements.
- Poorly fitting dentures should be adjusted or replaced.
- Drooling during sleep can be managed with anti-drooling prosthetic devices or other measures to reduce saliva accumulation.
- Immune suppression should be addressed through consultation with a healthcare provider to determine the best course of action.
Monitoring and Follow-up
If symptoms do not improve within two weeks of treatment, it is crucial to consult a healthcare provider for further evaluation and adjustment of the treatment plan as necessary.
- Regular follow-up appointments can help monitor the effectiveness of the treatment and identify any potential underlying causes that may need to be addressed.
- A comprehensive approach to treatment, including both topical and systemic therapies, as well as lifestyle modifications, can help improve outcomes and reduce the risk of recurrence.