When should a 58-year-old woman with a prior breast lumpectomy have her next Pap smear if her last Pap test was performed without concurrent HPV testing?

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Cervical Cancer Screening Timing for a 58-Year-Old Woman

This patient should have her next Pap smear in 3 years from her last test, since she had Pap testing alone without HPV co-testing. 1

Screening Recommendations for Women Aged 30-65 Years

For women in this age group, there are two acceptable screening strategies 2, 1:

  • Preferred approach: Co-testing with Pap plus HPV testing every 5 years 2, 1
  • Acceptable alternative: Pap testing alone every 3 years 2, 1

Since this patient had Pap testing alone without HPV co-testing, she falls into the "acceptable alternative" category and should continue screening every 3 years. 1

Critical Consideration: Breast Cancer History

The patient's history of breast cancer and lumpectomy does NOT alter cervical cancer screening recommendations. 2 Breast cancer history is not a risk factor that modifies cervical cancer screening intervals or protocols. 2 The screening schedule remains based solely on her age and the type of cervical cancer screening test performed. 1

When Screening Can Stop

This patient can discontinue cervical cancer screening after age 65 if she meets specific criteria 1, 3:

  • Either ≥3 consecutive negative Pap tests alone within the last 10 years 1, 3
  • Or ≥2 consecutive negative co-tests (Pap plus HPV) within the last 10 years, with the most recent test within the last 5 years 1, 3

Important Caveats

Do not screen annually - annual screening with any method is not recommended and increases harms without additional benefit. 2

Consider switching to co-testing - at her next visit, discuss transitioning to the preferred strategy of Pap plus HPV co-testing every 5 years, which would reduce screening frequency while maintaining equivalent or superior cancer detection. 1

Exceptions that would require continued screening past age 65 include 1, 4:

  • History of CIN2, CIN3, or adenocarcinoma in situ (requires 20 years of continued screening after treatment) 1, 4
  • Immunosuppression (HIV, transplant, chronic steroids) 1
  • History of cervical cancer 3

References

Guideline

Cervical Cancer Screening Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Screening Recommendations for a 71-Year-Old Female

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Cervical Cancer Screening Guidelines for Women with Abnormal Pap History

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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