What should a reproductive‑age woman with abdominal pain, a negative urinary‑tract infection test, a negative pregnancy test, and a non‑tender abdominal exam be advised to do for follow‑up and symptom management?

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Patient Information: Abdominal Pain with Negative UTI and Pregnancy Tests

You should schedule a gynecology follow-up appointment within 1-2 weeks and return to the emergency department immediately if you develop severe pain, fever, vomiting, or vaginal bleeding. 1

What Your Test Results Mean

  • Your negative pregnancy test effectively rules out pregnancy-related causes of your pain, including ectopic pregnancy. 1, 2
  • Your negative urinary tract infection test makes a bladder infection unlikely as the cause of your pain. 3
  • Your non-tender abdominal exam is reassuring and suggests you do not have an urgent surgical emergency at this time. 1

Why You Need Gynecology Follow-Up

Your symptoms require further evaluation by a gynecologist because many gynecologic conditions cannot be diagnosed by physical examination alone and need specialized imaging. 1

Possible Gynecologic Causes That Need Evaluation

  • Ovarian cysts or masses – These are common in reproductive-age women and can cause intermittent or persistent abdominal pain. 4
  • Pelvic inflammatory disease (PID) – This infection of the reproductive organs can present with mild, nonspecific symptoms and may not cause obvious tenderness on initial examination. 1
  • Endometriosis – This condition causes tissue similar to the uterine lining to grow outside the uterus and can cause chronic or cyclic pain. 4
  • Ovarian torsion – Though less common, this is a twisting of the ovary that requires urgent treatment. 1

What to Expect at Your Gynecology Appointment

Your gynecologist will likely order a pelvic ultrasound (both transvaginal and transabdominal) as the first imaging test, which is the most accurate way to evaluate gynecologic causes of abdominal pain without radiation exposure. 5, 1

  • Pelvic ultrasound is 93% sensitive and 98% specific for detecting tubo-ovarian abscesses. 1
  • It can also identify ovarian cysts, masses, and signs of endometriosis with high accuracy. 1, 4

Pain Management at Home

You may take ibuprofen 400 mg every 4-6 hours as needed for pain relief. 6

  • Take ibuprofen with food or milk to reduce stomach upset. 6
  • Do not exceed 3,200 mg (eight 400 mg tablets) in 24 hours. 6
  • If ibuprofen is not effective or you cannot take it, discuss alternative pain medications with your provider.

Warning Signs: Return to the Emergency Department Immediately If You Experience

  • Severe or worsening abdominal pain – This could indicate a complication requiring urgent imaging or surgery. 2, 4
  • Fever (temperature >100.4°F or 38°C) – This suggests possible infection requiring immediate treatment. 1
  • Persistent vomiting – This could indicate bowel obstruction or other serious conditions. 4
  • Vaginal bleeding – New bleeding could indicate a gynecologic emergency. 1
  • Dizziness, fainting, or rapid heartbeat – These symptoms could indicate internal bleeding. 1
  • Pain with urination or blood in urine – Your UTI test could have been falsely negative, particularly if symptoms develop. 7, 3

Important Considerations

  • False negative pregnancy tests can occur in up to 1.6% of cases, and are more common (3.6%) in women with abdominal pain. If your period is late or you develop vaginal bleeding, return for repeat pregnancy testing. 7
  • If your pain becomes generalized, severe, or you cannot keep down food/fluids before your gynecology appointment, go to the emergency department for a CT scan with IV contrast, which is the most accurate test for non-gynecologic causes of abdominal pain. 5, 2, 4
  • Do not ignore persistent or worsening symptoms – Many serious gynecologic conditions present with mild initial symptoms that progressively worsen. 1

Timeline for Follow-Up

  • Schedule your gynecology appointment within 1-2 weeks if your pain is mild and stable. 1
  • Call for an urgent appointment (within 24-48 hours) if your pain is moderate, interfering with daily activities, or associated with abnormal vaginal discharge. 1
  • Go to the emergency department immediately if you experience any of the warning signs listed above. 1, 2

References

Guideline

Diagnostic and Imaging Approach to Lower Pelvic Pain in Reproductive‑Age Women

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Imaging Guidelines for Persistent Abdominal Pain After Treated Ectopic Pregnancy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Diagnosis and treatment of urinary tract infections across age groups.

American journal of obstetrics and gynecology, 2018

Guideline

Diagnostic Evaluation of Intermittent Umbilical Pain in Reproductive‑Age Women

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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