Does Exercise Help With Your Health Problem?
Yes, exercise provides substantial health benefits across virtually all medical conditions, reducing mortality, improving disease-specific outcomes, and enhancing quality of life—you should engage in at least 150 minutes per week of moderate-intensity aerobic activity combined with strengthening exercises twice weekly. 1
Core Exercise Prescription
Target aerobic activity:
- Aim for at least 150 minutes per week of moderate-intensity aerobic exercise OR 75 minutes per week of vigorous-intensity exercise 1
- Spread activity across at least 3 days with no more than 2 consecutive days without exercise 1
- Each aerobic bout should ideally last at least 10 minutes 1
- Moderate-intensity means you can hold a conversation but breathing rate increases (brisk walking, cycling 8-15 km/h, swimming) 1
- Vigorous-intensity means conversation becomes difficult (jogging, cycling >16 km/h, competitive sports) 1
Add strengthening exercises:
- Perform resistance training at least twice weekly 1
- Target all major muscle groups with at least 5 different exercises per session 1
- Complete at least one set of each exercise 1
- Allow 48 hours rest between sessions for any single muscle group 2
Disease-Specific Benefits
For diabetes (type 1 and type 2):
- Exercise reduces A1C by an average of 0.66% even without weight loss 1
- Moderate to high volumes of aerobic activity substantially lower cardiovascular and overall mortality 1
- Daily exercise is recommended to decrease insulin resistance—do not allow more than 2 days between sessions 1
For rheumatic and musculoskeletal diseases:
- Exercise shows particularly strong effects for osteoarthritis and axial spondyloarthritis in reducing pain and improving function 1
- Both aerobic and strengthening exercises are necessary 1
- Exercise is safe with very few adverse events reported in studies 1
For cardiovascular disease prevention:
- Physical activity reduces cardiovascular mortality risk substantially 1
- Benefits include improved cardiorespiratory fitness, reduced blood pressure, and better lipid profiles 1
For cancer survivors:
- Exercise improves quality of life, reduces fatigue, and may reduce disease recurrence by up to 50% for certain cancers 1
- Benefits include improved cardiopulmonary fitness, muscle strength, and body composition 1
For people with disabilities:
- Exercise improves physical functioning, quality of life, and cognition across multiple conditions including multiple sclerosis, spinal cord injury, Parkinson's disease, and stroke 1
- Physical activity is safe when appropriate to individual ability level 1
Critical Safety Considerations
Pre-exercise assessment should identify:
- Uncontrolled hypertension, untreated proliferative retinopathy, autonomic neuropathy, peripheral neuropathy, or history of foot ulcers 1
- Severe anemia (delay exercise until improved) 1
- Compromised immune function (avoid public gyms/pools) 1
- Significant nutritional deficits or negative nitrogen balance 2
For diabetes-specific precautions:
- Check blood glucose before and after exercise if taking insulin or insulin secretagogues 1
- Ingest added carbohydrate if pre-exercise glucose <90 mg/dL (5.0 mmol/L) 1
- Be aware that hypoglycemia can occur hours after exercise due to increased insulin sensitivity 1
- Intense activity may raise blood glucose if pre-exercise levels are already elevated 1
Starting an Exercise Program
Begin conservatively:
- Start with short periods of low-intensity exercise and slowly increase intensity and duration as tolerated 1, 2
- Any increase in physical activity provides health benefits—even light activity is better than remaining sedentary 1
- It is never too late to start exercising, even if previously inactive 1
Choose sustainable formats:
- Exercise can be performed alone or in groups, with slight benefit favoring group settings for adherence 1
- Select activities that are enjoyable and fit your lifestyle 1
- Break up sedentary time (>30 minutes sitting) with brief standing or walking 1
Common Pitfalls to Avoid
Do not:
- Wait for "perfect" conditions to start—begin with whatever activity level is currently feasible 1
- Focus solely on weight loss as the goal—metabolic and cardiovascular benefits occur independent of weight change 1
- Exercise through severe fatigue, worsening pain, or new neurological symptoms 1, 3
- Allow more than 2 consecutive days without activity if managing insulin resistance 1
Do:
- Have regular discussions with healthcare professionals about exercise tolerance and modifications needed 1, 2
- Adjust intensity based on current health status, nutritional state, and individual tolerance 2
- Recognize that exercise complements but does not replace medical treatment 2
The Dose-Response Relationship
The relationship between physical activity and health outcomes is curvilinear—marked health benefits occur with relatively minor volumes of activity 4. Moving from completely sedentary to even modest activity levels provides the greatest proportional benefit 4. However, greater volumes and intensities of exercise provide additional benefits for A1C reduction, cardiorespiratory fitness, and mortality reduction 1.