What are the causes of seizures in a 6-month-old infant?

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Differential Diagnosis for 6 Month Old Seizure

Single Most Likely Diagnosis

  • Febrile Seizure: This is the most common cause of seizures in infants and young children, typically occurring between 6 months and 5 years of age. The seizure is usually triggered by a fever, often due to a viral infection.

Other Likely Diagnoses

  • Infection (Meningitis, Encephalitis): Bacterial or viral infections affecting the central nervous system can cause seizures in infants. Symptoms may include fever, irritability, and signs of increased intracranial pressure.
  • Metabolic Disorders: Conditions such as hypoglycemia, hypocalcemia, or electrolyte imbalances can precipitate seizures in infants. These disorders may be congenital or acquired.
  • Benign Familial Neonatal Epilepsy: Although less common, this genetic condition can cause seizures in the first few months of life, often with a family history of similar seizures.

Do Not Miss Diagnoses

  • Trauma (Non-Accidental Injury): It is crucial to consider the possibility of child abuse, especially if there are inconsistencies in the history or signs of physical trauma.
  • Intracranial Hemorrhage: Bleeding within the brain can cause seizures and is a medical emergency requiring immediate intervention.
  • Congenital Infections (TORCH): Infections such as toxoplasmosis, rubella, cytomegalovirus, and herpes simplex virus can cause neurological symptoms, including seizures, in newborns and infants.
  • Hyponatremia: Severe hyponatremia can lead to seizures and is potentially life-threatening if not promptly addressed.

Rare Diagnoses

  • Tuberous Sclerosis Complex: A genetic disorder characterized by the growth of non-cancerous tumors in various parts of the body, including the brain, which can cause seizures.
  • Infantile Spasms (West Syndrome): A rare and severe form of epilepsy that typically begins within the first year of life, often associated with developmental regression.
  • Pyridoxine-Dependent Epilepsy: A rare condition where seizures are resistant to conventional antiepileptic drugs but respond to pyridoxine (vitamin B6) supplementation.
  • Mitochondrial Disorders: A group of disorders affecting the mitochondria, which can cause a wide range of symptoms, including seizures, developmental delays, and muscle weakness.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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