Can the Richmond Agitation‑Sedation Scale (RASS) be used to assess sedation and agitation in pediatric patients, including critically ill children in the PICU?

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Last updated: February 24, 2026View editorial policy

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RASS Use in Pediatric Patients

The RASS is not the recommended primary sedation assessment tool for pediatric patients; instead, use the COMFORT Behaviour Scale, which has Grade A evidence for children aged 0-16 years. 1

Guideline-Recommended Pediatric Sedation Scales

The European Society of Paediatric and Neonatal Intensive Care (ESPNIC) provides clear guidance on sedation assessment tools for critically ill children:

  • The COMFORT Behaviour Scale is the primary recommended tool with Grade A evidence for pediatric patients aged 0-16 years, assessing alertness, calmness/agitation, respiratory response, physical movement, muscle tone, and facial tension. 1

  • The State Behavioural Scale is an alternative with Grade B evidence for children aged 6 weeks to 6 years. 1

  • RASS is not included in the ESPNIC guideline recommendations for pediatric sedation assessment, despite being the gold standard for adults. 1

Why RASS Is Not First-Line in Pediatrics

The COMFORT Behaviour Scale was specifically designed and validated for the pediatric population, addressing unique developmental considerations:

  • Children under 4 years comprise the majority of PICU patients and cannot self-report or understand their clinical situation, requiring behavioral assessment tools tailored to their developmental stage. 1

  • The COMFORT Behaviour Scale has established feasibility and utility at the bedside with proven validity, reliability, and clinical utility across the entire pediatric age range. 1

RASS Performance in Pediatric Research

While RASS is not guideline-recommended for pediatrics, recent research has examined its properties in children:

  • RASS demonstrates excellent inter-rater reliability in pediatric patients (weighted kappa 0.946) across ages 1 month to 18 years in a multicenter PICU study. 2

  • RASS shows high correlation with the COMFORT-B scale (rho = 0.935) and can distinguish between sedation levels in children. 2

  • RASS validity has been confirmed in critically ill children ages 2 months to 21 years, with excellent agreement compared to visual analog scales (Spearman 0.810) and high inter-rater reliability (weighted kappa 0.825). 3

  • Educational interventions significantly improve RASS reliability in pediatrics, increasing weighted kappa from 0.56 to 0.86, including in infants under 1 year and children with developmental delay. 4

Clinical Implementation Guidance

If your institution uses RASS in pediatrics despite guideline recommendations:

  • Ensure comprehensive staff education before implementation, as this dramatically improves inter-rater reliability from moderate to excellent levels. 4

  • Assess sedation every 4-8 hours alongside vital signs, with more frequent monitoring during active sedation adjustments or clinical instability. 1

  • Always evaluate for underlying causes of agitation first (pain, ventilator maladjustment, environmental factors) before escalating sedatives. 1, 5

Critical Pitfalls to Avoid

  • Do not assume adult sedation tools automatically apply to children—pediatric-specific validated scales exist for good reason and carry higher-grade evidence. 1

  • Do not rely solely on clinical judgment without a validated assessment tool, as this leads to inconsistent sedation management and suboptimal outcomes. 1, 5

  • Do not overlook that 32% of pediatric observations show oversedation, which prolongs mechanical ventilation and increases healthcare costs. 1

  • Do not use RASS without proper training—untrained staff show only moderate reliability (kappa 0.56), which improves to excellent (kappa 0.86) after education. 4

Bottom Line for Practice

Use the COMFORT Behaviour Scale as your primary sedation assessment tool in pediatric ICU patients, as it carries Grade A recommendations from ESPNIC and was specifically designed for children. 1, 5 If your institution has already implemented RASS with comprehensive staff education and demonstrated excellent reliability, it may be used as an alternative, but this represents off-guideline practice. 2, 4, 3

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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