What is the cause of a patient's bilateral ear pain, sore throat, and hearing difficulty?

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Last updated: April 24, 2025View editorial policy

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Differential Diagnosis for Bilateral Ear Pain

  • Single most likely diagnosis
    • Eustachian tube dysfunction: The patient's symptoms of ear pain, feeling of needing to "pop" their ears, and difficulty hearing are consistent with Eustachian tube dysfunction, which can be caused by a variety of factors including allergies, colds, or sinus infections. The mild sore throat also supports this diagnosis.
  • Other Likely diagnoses
    • Otitis media with effusion (OME): The patient's symptoms of ear pain, difficulty hearing, and feeling of fullness in the ears could be consistent with OME, which is a common condition in adults and children.
    • Otitis externa: Although the patient does not report any discharge or itching, otitis externa is still a possible diagnosis, especially if the patient has been swimming or using earbuds.
    • Temporomandibular joint (TMJ) disorder: The patient's report of pain at the bottom of the ears and neck could be referred pain from the TMJ, which is a common cause of ear pain.
  • Do Not Miss diagnoses
    • Malignancy (e.g. nasopharyngeal carcinoma): Although rare, malignancies in the head and neck region can cause Eustachian tube dysfunction and ear pain, and would be devastating if missed.
    • Acoustic neuroma: A benign tumor on the vestibulocochlear nerve can cause ear pain, hearing loss, and balance problems, and would require prompt diagnosis and treatment.
    • Lyme disease: If the patient has been exposed to ticks, Lyme disease could be a possible diagnosis, as it can cause ear pain, hearing loss, and other systemic symptoms.
  • Rare diagnoses
    • Relapsing polychondritis: A rare autoimmune disorder that can cause ear pain, hearing loss, and other systemic symptoms.
    • Wegener's granulomatosis: A rare autoimmune disorder that can cause ear pain, hearing loss, and other systemic symptoms, including respiratory and renal involvement.
    • Otosclerosis: A rare condition that causes abnormal bone growth in the middle ear, leading to hearing loss and ear pain.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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