What can be given to a 5-year-old child for nausea and vomiting?

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Management of Nausea and Vomiting in a 5-Year-Old Child

For a 5-year-old with nausea and vomiting, begin oral rehydration solution (ORS) immediately using small, frequent volumes of 5 mL every 1–2 minutes via spoon or syringe, and consider ondansetron 4 mg orally if vomiting persists and interferes with oral intake. 1, 2, 3

Initial Assessment and Fluid Management

Assess dehydration severity first by examining skin turgor, mucous membrane moisture, mental status, capillary refill, and urine output to classify as mild (3–5% deficit), moderate (6–9% deficit), or severe (≥10% deficit). 2

Oral Rehydration Strategy

  • Start ORS immediately using the slow-administration technique: give 5 mL every 1–2 minutes with a spoon or syringe under close supervision. 1, 2
  • This gradual approach succeeds in >90% of children with vomiting and prevents triggering additional emesis that occurs when children drink rapidly from a cup. 1, 2
  • For mild dehydration, administer approximately 50 mL/kg of low-osmolarity ORS over 2–4 hours. 2
  • For moderate dehydration, increase to 100 mL/kg over 2–4 hours. 2
  • Replace ongoing losses with 10 mL/kg for each watery stool and 2 mL/kg for each vomiting episode. 2
  • Reassess after 2–4 hours; if still dehydrated, recalculate the deficit and restart the protocol. 2

Ondansetron Use

Ondansetron may be administered to children ≥4 years when vomiting is significant and interferes with oral rehydration. 2, 3

  • Dosing: Give 4 mg orally as a single dose 30 minutes before attempting ORS. 3, 4
  • Benefit: Reduces vomiting episodes, facilitates oral intake, and decreases the need for intravenous hydration. 2, 5, 4
  • Important caveat: Ondansetron may increase the number of diarrhea episodes, but this trade-off is acceptable when vomiting prevents rehydration. 4
  • Monitor for QTc prolongation if the child has electrolyte abnormalities (hypokalemia, hypomagnesemia) or is taking other QT-prolonging medications. 3

Dietary Management

  • Resume a normal, age-appropriate diet immediately during or after rehydration; do not withhold food. 1, 2
  • Recommended foods include starches (rice, potatoes, noodles), cereals, yogurt, fruits, and vegetables. 1, 2
  • Avoid high-sugar drinks (soft drinks, undiluted fruit juice, sports drinks) and high-fat foods, as they worsen diarrhea through osmotic effects and delayed gastric emptying. 1, 2

Medications to Avoid

  • Never give loperamide or any antimotility agent to children under 18 years; serious adverse events including ileus and death have been reported. 2
  • Do not use adsorbents, antisecretory drugs, or toxin binders; they are ineffective and divert attention from proper fluid therapy. 1, 2
  • Antibiotics are not indicated for typical viral gastroenteritis; reserve them for bloody diarrhea with high fever, systemic toxicity, or confirmed bacterial pathogens. 1, 2

When to Seek Immediate Medical Care

Bring the child to the emergency department if any of the following develop:

  • Severe dehydration signs: altered consciousness, prolonged skin tenting (>2 seconds), cool extremities, poor capillary refill, or rapid deep breathing. 2
  • Bilious (green) vomiting, which suggests intestinal obstruction. 2
  • Bloody stools with fever, indicating possible bacterial dysentery. 2
  • Persistent vomiting despite ondansetron and proper ORS technique. 2
  • Decreased urine output, severe lethargy, or irritability. 1, 2

Intravenous Therapy (Hospital Setting Only)

  • Reserve IV fluids for severe dehydration (≥10% deficit), shock, altered mental status, or failure of oral rehydration. 2
  • Administer 20 mL/kg boluses of lactated Ringer's or normal saline until pulse, perfusion, and mental status normalize, then transition to ORS. 2

Common Pitfalls to Avoid

  • Do not allow the child to drink large volumes rapidly from a cup; this triggers vomiting and falsely suggests ORS failure. 2
  • Do not use sports drinks or juice as rehydration fluids; they lack appropriate electrolyte balance. 2
  • Do not withhold food or enforce fasting; early refeeding shortens illness duration. 1, 2
  • Do not delay rehydration while awaiting diagnostic tests; start ORS based on clinical assessment. 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Gastroenteritis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Pediatric rapid fluid resuscitation.

Current opinion in pediatrics, 2011

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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