Trade Name for Fondaparinux
Fondaparinux is marketed under the trade name Arixtra. 1
Key Product Information
- Generic name: Fondaparinux sodium 2, 3
- Brand name: Arixtra 1, 2
- Manufacturer: Sanofi-Synthelabo (now part of Sanofi) 4
- Drug class: Synthetic pentasaccharide, selective factor Xa inhibitor 5, 2, 4
Clinical Context
Arixtra (fondaparinux) is FDA-approved for:
- Prophylaxis of venous thromboembolism (VTE) following major orthopedic surgery 6, 2
- Treatment of acute deep vein thrombosis and pulmonary embolism 5, 7
- Treatment of acute coronary syndromes (in combination with other therapies) 8
The medication is administered as a once-daily subcutaneous injection due to its 17-21 hour half-life, which distinguishes it from low-molecular-weight heparins that often require twice-daily dosing. 5, 3