From the Research
The MPV (Mean Platelet Volume) value of 12.1 fL is elevated above the normal range, which is typically 7.5-11.5 fL, and is flagged as high at 12.7, indicating a potential increased risk of cardiovascular events and other conditions associated with increased platelet activity, as suggested by a study published in 2013 1. This indicates larger than normal platelets in your bloodstream. Elevated MPV is associated with increased platelet activity and can be seen in conditions like cardiovascular disease, diabetes, inflammatory disorders, or following recovery from bone marrow suppression. Some key points to consider include:
- Elevated MPV has been linked to increased infarct size and microvascular obstruction in patients with ST-segment elevation myocardial infarction, as shown in a study published in 2013 1.
- Desmopressin may be a useful agent to reduce bleeding and transfusion requirements for people with platelet dysfunction or with a history of recent antiplatelet drug administration undergoing cardiac surgery, as suggested by a study published in 2017 2.
- Lifestyle modifications such as regular exercise, maintaining a healthy weight, and following a heart-healthy diet may be beneficial, especially if cardiovascular risk factors are present. No immediate medication is required specifically for an elevated MPV, but it warrants follow-up with your healthcare provider to determine the underlying cause. Additional blood tests may be recommended, including a complete blood count to assess platelet numbers and other blood cell parameters. The elevated MPV should be interpreted in the context of your overall health status, symptoms, and other laboratory findings to determine its clinical significance, and more recent studies such as those from 2020 3 and 2014 4 provide further insights into the management of platelet dysfunction.