Is there a relationship between carpal tunnel syndrome and hypothyroidism?

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Last updated: February 16, 2025View editorial policy

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From the Research

Relationship between Carpal Tunnel Syndrome and Hypothyroidism

  • There is evidence to suggest a relationship between carpal tunnel syndrome (CTS) and hypothyroidism, with several studies indicating that hypothyroidism is a risk factor for CTS 1, 2.
  • A study published in the Journal of Clinical and Diagnostic Research found that 16.7% of patients with primary hypothyroidism had CTS, and that increased body mass index (BMI) and presence of clinical symptoms and/or signs of CTS were independently correlated with the presence of CTS in hypothyroidism 1.
  • Another study published in The Journal of Hand Surgery found that 73% of hypothyroid patients displayed symptoms of CTS, and that normal median nerve latencies at the wrist in the presence of CTS symptoms and a positive physical examination were more prevalent than expected in hypothyroid patients 2.
  • However, it's worth noting that not all studies have found a significant relationship between CTS and hypothyroidism, and that the evidence is not yet conclusive 3, 4, 5.

Clinical Implications

  • The relationship between CTS and hypothyroidism has important clinical implications, as it suggests that patients with hypothyroidism may be at increased risk of developing CTS 1, 2.
  • Clinicians should be aware of this potential relationship and consider screening patients with hypothyroidism for CTS symptoms and signs 1, 2.
  • Further research is needed to fully understand the relationship between CTS and hypothyroidism, and to determine the best course of treatment for patients with both conditions 3, 4, 5.

References

Research

Carpal Tunnel Syndrome in Hypothyroidism.

Journal of clinical and diagnostic research : JCDR, 2016

Research

Effectiveness of surgical versus conservative treatment for carpal tunnel syndrome: A systematic review, meta-analysis and qualitative analysis.

Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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