What is the diagnosis for a 25-year-old patient with colitis (inflammation of the colon) and ileitis (inflammation of the ileum), presenting with abdominal pain, diarrhea, and vomiting?

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Last updated: April 25, 2025View editorial policy

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Differential Diagnosis for Colitis and Ileitis

Single Most Likely Diagnosis

  • Inflammatory Bowel Disease (IBD): Given the symptoms of abdominal pain, diarrhea, and vomiting in a 25-year-old, IBD (which includes Crohn's disease and ulcerative colitis) is a strong consideration due to its peak incidence in young adults and the nature of the symptoms presented.

Other Likely Diagnoses

  • Infectious Colitis: Bacterial, viral, or parasitic infections can cause similar symptoms and are common in young adults, especially if there's a history of travel, antibiotic use, or exposure to contaminated food and water.
  • Irritable Bowel Syndrome (IBS): Although IBS typically doesn't cause vomiting, it can cause abdominal pain and diarrhea, and its diagnosis should be considered, especially if there's a pattern of symptom exacerbation with stress or certain foods.
  • Food Poisoning: Acute onset of symptoms like vomiting, diarrhea, and abdominal pain could suggest food poisoning, which is a common condition that can affect anyone.

Do Not Miss Diagnoses

  • Appendicitis: Although the primary symptom is usually abdominal pain, vomiting and diarrhea can occur, especially if the appendix ruptures. Missing this diagnosis can lead to severe complications.
  • Intussusception: A condition where a part of the intestine slides into an adjacent part, which can cause bowel obstruction and ischemia. It's rare in adults but can present with abdominal pain, vomiting, and diarrhea.
  • Mesenteric Ischemia: Reduced blood flow to the intestines can cause severe abdominal pain, vomiting, and diarrhea. It's a medical emergency that requires prompt diagnosis and treatment.

Rare Diagnoses

  • Eosinophilic Gastroenteritis: A rare condition characterized by eosinophilic infiltration of the gastrointestinal tract, which can cause abdominal pain, vomiting, and diarrhea.
  • Behçet's Disease: A form of vasculitis that can affect the gastrointestinal tract, among other systems, causing symptoms like abdominal pain, diarrhea, and vomiting, although it's more commonly associated with oral and genital ulcers.
  • Gastrointestinal Lymphoma: A rare type of cancer that can cause a variety of gastrointestinal symptoms, including abdominal pain, vomiting, and diarrhea, especially if the ileum is involved.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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