What is the target drop of glucose in Hyperosmolar Hyperglycemic State (HHS)?

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From the FDA Drug Label

The intravenous administration of Humulin R U-100 was tested in 21 patients with type 1 diabetes ... adjusted to maintain blood glucose concentrations near normoglycemia (100 to 160 mg/dL). The mean blood glucose levels during the assessment phase for patients on Humulin R U-100 therapy ... The average time (± SE) required to attain near normoglycemia was 161 ± 14 minutes for Humulin R U-100. At the endpoint, blood glucose was within the target range (100 to 160 mg/dL) for 20 of 21 patients treated with Humulin R U-100.

The target drop of glucose in Hyperosmolar Hyperglycemic State (HHS) is not directly mentioned in the provided drug label. However, for normoglycemia, the target range is 100 to 160 mg/dL.

  • The study does not explicitly address HHS, but it does provide a target range for normoglycemia.
  • The provided information does not allow for a direct conclusion about the target drop of glucose in HHS. 1

References

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