What does hepatitis A virus infection look like on the genitals?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 25, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Hepatitis A Does Not Cause Genital Lesions

Hepatitis A virus (HAV) does not produce any visible manifestations on the genitals. HAV is a liver infection transmitted by the fecal-oral route, not a sexually transmitted infection that causes genital lesions 1.

Why This Question Reflects a Common Misunderstanding

You may be confusing HAV with other conditions that do cause genital lesions:

  • Herpes Simplex Virus (HSV-2) causes painful genital ulcers and blisters
  • Human Papillomavirus (HPV) causes genital warts (flesh-colored, raised lesions) 1
  • Syphilis causes painless genital ulcers (chancres)

How Hepatitis A Actually Presents

HAV affects the liver, not the skin or genitals. The clinical manifestations include 1:

  • Systemic symptoms: Jaundice (yellowing of skin/eyes), dark urine, pale stools, fatigue, nausea, vomiting, abdominal pain 2, 3
  • No skin lesions: HAV does not cause any rashes, ulcers, warts, or other visible skin changes on the genitals or elsewhere 1
  • Age-dependent presentation: Approximately 70% of adults develop symptomatic acute viral hepatitis, while most children have asymptomatic or unrecognized infection 1

Transmission Context That May Cause Confusion

HAV can be transmitted during sexual activity, but only through fecal-oral contact—not through genital-to-genital contact. 1

  • Transmission occurs when fecal material containing the virus enters the mouth, which can happen during certain sexual practices (particularly oral-anal contact) 1
  • Men who have sex with men (MSM) are at higher risk for HAV transmission during sexual activity 1
  • Standard STD prevention measures like condoms do not prevent HAV transmission because the virus is spread fecal-orally, not through genital secretions 1

Critical Clinical Distinction

If you see lesions on the genitals, you are NOT looking at hepatitis A. 1

  • HAV replicates in the liver and is shed in high concentrations in feces from 2-3 weeks before to 1 week after symptom onset 1
  • The incubation period averages 28 days (range: 15-50 days) 1, 4
  • Diagnosis requires serologic testing (IgM anti-HAV for acute infection), not visual inspection of the genitals 1

What to Do If You're Concerned About Genital Lesions

Seek evaluation for actual STDs that cause genital lesions:

  • HSV testing for painful ulcers/blisters
  • HPV evaluation for warts 1
  • Syphilis serology for painless ulcers
  • Consider HAV vaccination if you're in a high-risk group (MSM, injection drug users, persons with chronic liver disease), but this is for liver protection, not genital lesion prevention 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Natural History, Clinical Manifestations, and Pathogenesis of Hepatitis A.

Cold Spring Harbor perspectives in medicine, 2018

Research

Hepatitis A: old and new.

Clinical microbiology reviews, 2001

Guideline

Natural History of Hepatitis A Virus Infection

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.