NPWT Application to Repaired Stoma Sites with Necrosis
Yes, negative pressure wound therapy can and should be applied to repaired stoma sites complicated by necrosis, with the primary goal of managing wound output, protecting surrounding skin, and promoting granulation tissue formation for eventual closure. 1, 2
Clinical Rationale for NPWT Use
NPWT is specifically recommended for managing complex stoma-related wounds with necrosis because it addresses multiple critical problems simultaneously:
- Controls effluent and protects peristomal skin from breakdown, which is the primary goal when managing enteric fistulae and stoma complications 1
- Promotes granulation tissue formation in necrotic wound beds, creating conditions favorable for healing 3
- Provides a "splinting effect" that stabilizes the wound and anchors drainage tubes close to the stoma opening without causing bowel damage 3, 1
- Actively drains fluid (typically 800ml or more) preventing pooling and maceration of surrounding tissue 3
Technical Application Strategy
Step 1: Isolate the Stoma
- Create a "floating stoma" by isolating the functional stoma opening with an ostomy bag 3, 1
- NPWT is often the only method that achieves secure ostomy bag adhesion in these complex wounds, particularly in mobile patients 3, 1
Step 2: Protect Exposed Bowel
- Always apply a non-adherent interface layer directly over any exposed bowel or anastomotic tissue to prevent fistula formation during dressing changes 3
- This is a critical safety step—failure to use this layer exposes the patient to significant risk of iatrogenic fistula formation 3
Step 3: Apply NPWT to Peristomal Wound
- Place foam dressing in the necrotic cavity around the stoma (not directly on the stoma itself) 2, 4
- Use continuous negative pressure settings of 75-125 mmHg—higher pressures improve fluid drainage but must be balanced against potential bowel injury 3, 4
- Pressures up to -125 mmHg have been well-tolerated even in neonates with complex stoma wounds 4
Step 4: Manage Effluent
- If viscous output pools beneath the foam, create a conduit from the effluent source through the dressing to the canister using either an ostomy bag or drain (such as a Malecot catheter) 3, 1, 4
- This prevents contamination of the wound bed while maintaining negative pressure 4
Expected Outcomes and Timeline
- Wound closure typically occurs within 14-30 days of NPWT application 2, 5
- One case series demonstrated complete closure at day 30 in a patient with colostomy necrosis and stoma retraction 2
- Another report showed complete healing by postoperative day 14 in a highly contaminated wound with multiple fistulas around a colonic stoma 5
Skin Protection Protocol
While NPWT is managing the wound, concurrent skin protection is essential:
- Apply zinc oxide-based barrier cream, paste, or film to all peristomal skin before NPWT application 1, 6
- Use foam dressings (not gauze) for additional absorption—foam lifts drainage away from skin while gauze contributes to maceration 7, 6
- Place an adhesive skin sealant over the barrier before fitting the NPWT to add extra protection 7
Critical Pitfalls to Avoid
- Never apply NPWT directly to exposed bowel without a non-adherent interface layer—this will cause fistula formation 3
- Do not use intermittent or variable pressure settings—these compromise the splinting effect essential for wound stability 3
- Avoid using surgical towels or gauze as wound filler instead of foam—these materials do not compress under pressure and fail to provide the medial traction needed for closure 3
- Do not initiate NPWT if there is uncontrolled intra-abdominal sepsis—drain any abscesses first with antibiotics and radiological drainage 1, 6
When to Transition from NPWT
Once NPWT has achieved:
- Control of effluent output
- A healthy granulating wound bed
- Resolution of necrotic tissue
Consider skin grafting for any remaining defects that cannot close by secondary intention 1
Evidence Quality Note
The strongest evidence comes from International Journal of Surgery guidelines (2014) providing Grade B-D recommendations for NPWT in complex abdominal and stoma wounds 3. These are supported by multiple case reports demonstrating successful outcomes in exactly this clinical scenario 2, 5, 4, and recent studies showing reduced surgical site infection rates when NPWT is applied to stoma sites 8, 9.