How can I clear a clogged gastrostomy (G) tube that is not flushing?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 25, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Management of Clogged Gastrostomy Tube

Start by flushing the clogged G-tube with 40-60 mL of warm water using gentle pressure, which successfully clears approximately one-third of obstructions. 1

Stepwise Algorithmic Approach

Step 1: Initial Water Flush

  • Position the patient upright to minimize aspiration risk during the procedure 2, 3
  • Attempt to flush with 40-60 mL of warm water using gentle pressure 2, 3
  • Never force the flush if you encounter significant resistance, as this can damage or rupture the tube 3
  • This simple intervention resolves the obstruction in approximately 33% of cases 1

Step 2: Pancreatic Enzyme Installation

If water flushing fails, instill an alkaline solution of pancreatic enzymes, which reopens an additional 50% of occluded tubes. 1

  • Mix pancreatic enzyme capsules (such as Creon) with sodium bicarbonate solution to create an alkaline environment 2, 4
  • The alkaline pancreatic enzyme solution demonstrates a 96% success rate specifically for formula-related clogs 2, 5
  • Allow the enzyme solution to dwell in the tube for optimal effect 5
  • Important caveat: Recent studies using reformulated pancreatic enzymes (Creon delayed-release capsules) show lower efficacy (48%) compared to older formulations (Viokase at 72%), but this remains the best pharmacologic option 4, 5

Step 3: Mechanical Devices

If enzymatic treatment fails, attempt mechanical clearance using: 1

  • Fogarty balloon catheter 1
  • Biopsy brush 1
  • Commercially available tube decloggers (actuated mechanical devices show 93% success rates in bench studies) 6
  • A soft guidewire may be passed carefully to avoid tube perforation 3

Step 4: Tube Replacement

Replace the tube only as a last resort after all other methods have failed. 1, 3

Critical Interventions to Avoid

  • Do not use carbonated beverages, cranberry juice, or pineapple juice, as these are inferior to water and can degrade tube material 1, 3
  • Avoid excessive force when attempting to clear blockages, which may rupture the tube 3
  • Do not use hydrogen peroxide for tube maintenance, as it irritates skin and contributes to stomal leaks 1

Prevention Strategies for Future Clogs

Implement routine flushing with 40 mL of water before and after every feed or medication administration. 2, 3

  • Flush with water every 4 hours during continuous feeding 7
  • Use sterile water for flushing when possible, as tap water has been associated with infections 1
  • Administer medications in liquid form rather than crushed tablets when possible 3
  • Rotate and loosen the gastrostomy tube weekly to prevent blockage from gastric mucosal overgrowth 3
  • Never mix medications together; administer individually with water flushes between each 7

Common Pitfalls

  • G-tube occlusion occurs in 20-45% of cases, with rates increasing 10-fold if gastric residuals are checked through the feeding tube 1
  • The main cause of tube failure in balloon-type tubes is occlusion, while distensible bumper-type tubes fail primarily from tube degradation 1
  • Hyperosmolar drugs, crushed tablets, and certain supplements are particularly likely to cause blockages 3
  • Protein-based formulas interacting with acidic gastric environment and medications are common causes of occlusion 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Unclogging a Jejunal Tube

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of PEG Tube Blockages

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Unclogging feeding tubes with pancreatic enzyme.

JPEN. Journal of parenteral and enteral nutrition, 1990

Research

Enteral Feeding Tube Clogging: What Are the Causes and What Are the Answers? A Bench Top Analysis.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2018

Guideline

Nasogastric Tube Flushing Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.