How long does a midline catheter last?

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Last updated: February 16, 2025View editorial policy

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From the Guidelines

The duration of midline catheter placement typically ranges from 1 to 4 weeks, with an average dwell time of 14 to 21 days 1.

Key Points

  • Midline catheters are often used for intermediate-term intravenous therapy, such as administering antibiotics like ceftriaxone or vancomycin, and may be replaced or removed once the treatment course is completed, usually after 2 to 4 weeks of continuous use.
  • In general, midline catheters are not intended for long-term use, and their duration is limited by the risk of complications, including catheter-related bloodstream infections and thrombophlebitis.
  • According to the Michigan Appropriateness Guide for Intravenous Catheters (MAGIC), midline catheters are rated as appropriate for 14 or fewer days of use 1.
  • The ESPEN guidelines on parenteral nutrition recommend considering midline catheters as a potential option when peripheral therapy is expected for more than 6 days, and stress the importance of careful surveillance for thrombophlebitis 1.

Important Considerations

  • The risk of complications, such as catheter-related bloodstream infections and thrombophlebitis, increases with the duration of midline catheter placement.
  • Midline catheters should be used for intermediate-term intravenous therapy, and their duration should be limited to 1 to 4 weeks.
  • The decision to use a midline catheter should be based on the individual patient's needs and the expected duration of therapy.

From the Research

Midline Catheter Duration

The duration of a midline catheter can vary depending on several factors, including the patient's condition, the type of infusion, and the catheter's maintenance.

  • The median dwell time for midline catheters was 11 days (interquartile range, 5.5-19.5 days) in a study published in the American Journal of Infection Control 2.
  • A prospective observational pilot study published in Anesthesia and Analgesia found that the median catheter dwell time for pediatric midline catheters was 6 days (range, 4-8 days) 3.
  • Another study published in the Journal of Critical Care reported an average midline dwell time of 14.7 ± 12.8 days for patients receiving vasopressors via midline catheters 4.
  • A pilot randomized clinical trial published in Nursing Reports found that midline catheters had a longer duration of cannulation (8.13 days) compared to peripheral intravenous catheters (3.22 days) 5.

Factors Affecting Midline Catheter Duration

Several factors can affect the duration of a midline catheter, including:

  • Patient characteristics, such as age and comorbidities 6
  • Type of infusion, such as antibiotics or vasopressors 2, 4
  • Catheter maintenance and care 2, 5
  • Insertion site, with arm vein insertion potentially having a lower risk of complications compared to saphenous vein insertion 3

Complications and Midline Catheter Duration

Complications can also impact the duration of a midline catheter.

  • A study published in the American Journal of Infection Control found that catheter-related complications occurred in 23.5% of patients, including catheter dislodgement, kinking, and occlusion 2.
  • Another study published in Anesthesia and Analgesia reported that catheter-related venous thromboembolism (VTE) occurred in 30% of pediatric midline catheters 3.
  • A study published in the Journal of Critical Care found that the early complication rate for midline catheters was 3.6%, with late complications occurring in 0.8% of patients 4.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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