Is a urine protein-to-creatinine ratio of 159.25 mg/g indicative of proteinuria?

Haan, aapke urine mein protein aa raha hai

Aapka protein/creatinine ratio 159.25 mg/g hai, jo normal range (200 mg/g se kam) ke bilkul neeche hai, lekin yeh borderline elevated hai aur isko confirm karne ki zaroorat hai. 1

Aapke Result ka Matlab

• Normal range: Protein/creatinine ratio 200 mg/g se kam hona chahiye 2, 1
• Aapka result: 159.25 mg/g technically normal range mein hai, lekin yeh upper limit ke kareeb hai
• Clinical significance: Yeh level suggest karta hai ki aapko mild proteinuria ho sakta hai jo confirm karne ki zaroorat hai 1

Agle Kadam – Confirmation Zaroori Hai

Ek single test se diagnosis nahi karna chahiye. Aapko repeat testing karwani hogi kyunki proteinuria temporary bhi ho sakta hai: 1, 3

Repeat Test Kab Aur Kaise Karwayein

• 3 mahine ke andar doosra test karwayein – subah ka pehla urine sample use karein 1
• Persistent proteinuria tab confirm hota hai jab 3 samples mein se 2 positive aayein 1
• Test se pehle 24 ghante tak heavy exercise avoid karein 1
• Fever, infection, ya bimari ke time test na karwayein kyunki yeh temporarily protein badha sakta hai 1

Transient (Temporary) Causes Jo Exclude Karne Hain

Yeh cheezein temporarily protein badha sakti hain: 1

• Urinary tract infection (UTI) – pehle infection ka treatment karwayein, phir retest karein
• Heavy exercise – test se 24 ghante pehle avoid karein
• Fever ya acute illness
• Menstruation (mahilaaon mein)

Risk Factors Check Karein

Agar aapko yeh conditions hain to annual monitoring zaroori hai: 1

• Diabetes
• High blood pressure (hypertension)
• Family history of kidney disease
• Age > 60 years

Kidney Function Test Bhi Karwayein

Proteinuria ke saath serum creatinine aur eGFR check karna zaroori hai: 2, 1

• eGFR (estimated Glomerular Filtration Rate) kidney function batata hai
• Yeh CKD-EPI equation se calculate hota hai 2
• eGFR < 60 mL/min/1.73 m² ko "decreased" report kiya jata hai 2

Kab Doctor Ko Dikhana Zaroori Hai

Turant nephrologist ko dikhayein agar: 1

• Repeat test mein protein/creatinine ratio ≥1000 mg/g (1 g/g) aaye
• Nephrotic range (>3500 mg/g) proteinuria ho
• eGFR < 30 mL/min/1.73 m² ho
• Urine mein blood (hematuria) bhi ho
• Swelling (edema) ho

Common Pitfalls Se Bachein

• Ek hi test pe depend na karein – confirmation zaroori hai 1
• 24-hour urine collection routine mein zaroori nahi hai – spot urine protein/creatinine ratio kaafi accurate hai 1, 3
• First morning sample sabse reliable hota hai 1

Practical Algorithm

Step 1: Transient causes exclude karein (UTI, exercise, fever)
         ↓
Step 2: 3 mahine ke andar repeat test – first morning void
         ↓
Step 3: Agar 3 mein se 2 tests positive (≥200 mg/g)
         ↓
Step 4: Serum creatinine aur eGFR check karein
         ↓
Step 5: Agar persistent proteinuria confirmed hai:
        - Moderate (200-1000 mg/g): Conservative management
        - High (>1000 mg/g): Nephrology referral

Bottom line: Aapka current result borderline hai aur isko seriously lena chahiye, lekin panic karne ki zaroorat nahi. Proper confirmation ke liye repeat testing karwayein aur kidney function check karwayein. 1, 3