Treatment of Ingrown Toenails
Start with conservative management using antiseptic soaks and topical steroids for mild cases, escalate to partial nail avulsion with phenolization for moderate-to-severe or treatment-refractory cases after 2 weeks of failed conservative therapy. 1, 2
Initial Conservative Management (First-Line for Mild Cases)
Antiseptic Soaks and Topical Therapy
- Perform warm antiseptic soaks twice daily for 10-15 minutes using either dilute vinegar (50:50 dilution) or 2% povidone-iodine solution 1, 2
- Apply topical 2% povidone-iodine twice daily to the affected area as the most evidence-based antiseptic 3
- Use mid-to-high potency topical corticosteroid ointment to nail folds twice daily immediately after soaking to reduce inflammation and edema 1, 2
- Stop topical steroids immediately if purulent drainage develops 1, 3
Mechanical Relief Techniques
- Gutter splinting with a plastic tube placed on the lateral nail edge provides immediate pain relief 1, 2
- Cotton wisp or dental floss insertion under the ingrown lateral nail edge separates it from underlying inflamed tissue 2, 4
- Taping the lateral nail fold away from the nail plate reduces pressure 1, 3
Antibiotic Therapy (When Infection is Present)
Indications for Antibiotics
- Do not routinely prescribe antibiotics unless clear signs of infection are present, such as purulent drainage or cellulitis extending beyond the nail fold 2
- Up to 25% of cases develop bacterial or fungal superinfections requiring antimicrobial therapy 1, 3
Antibiotic Selection
- Start with cephalexin as first-line therapy for mild-to-moderate infections 1
- Amoxicillin-clavulanate is an alternative first-line option 3
- Switch to sulfamethoxazole-trimethoprim (Bactrim) if initial treatment fails, providing broader coverage including MRSA 1
- Continue antibiotics for 1-2 weeks for mild infections; moderate-to-severe infections may require 2-4 weeks 3
- For recurrent, severe, or treatment-refractory cases, use doxycycline 100 mg twice daily with follow-up after one month 2
Surgical Intervention
Timing and Indications
- Reassess after 2 weeks of conservative management 2, 3
- Escalate to surgical consultation if no improvement after 2 weeks of appropriate conservative therapy 2, 3
- Partial nail avulsion is indicated for intolerable pain despite conservative management or when pain persists beyond 2-4 weeks 1, 3
- Immediate surgical consultation is required for severe infections with deep abscess, extensive tissue involvement, or substantial necrosis 3
Surgical Approach
- Partial nail avulsion followed by phenolization is more effective at preventing symptomatic recurrence compared to surgical excision alone, though it carries a slightly increased risk of postoperative infection 5
- Partial nail avulsion with either phenolization or direct surgical excision of the nail matrix are equally effective treatment options 5
Management of Granulation Tissue
- Scoop shave removal with hyfrecation or silver nitrate application for pyogenic granuloma formation 1
- High-potency topical steroids or topical timolol 0.5% gel twice daily under occlusion can be considered 1
- Intralesional triamcinolone acetonide for recurrent or severe cases 1
Prevention of Recurrence
Patient Education (Critical Component)
- Trim toenails straight across, not too short, and avoid cutting into corners 2, 3
- Wear comfortable, well-fitting shoes with adequate toe box and cotton socks 1, 3
- Apply topical emollients daily to cuticles and periungual tissues 2
- Avoid manipulating cuticles or using nails as tools 2
- Wear protective gloves when working with water or chemicals 1, 2
Special Population: Diabetic Patients
- Diabetic patients require more aggressive monitoring and prompt treatment by trained healthcare professionals 2
- Ingrown toenails can progress to foot ulceration with significant morbidity in diabetics 2
- Provide integrated foot care every 1-3 months for diabetic patients 2
Critical Pitfalls to Avoid
- Do not delay surgical intervention beyond 2 weeks if medical management fails 3
- Do not use topical steroids in the presence of purulent drainage 1, 3
- Do not prescribe clindamycin as first-line therapy 3
- Oral antibiotics before or after phenolization do not improve outcomes and should not be routinely used 5