From the Guidelines
For seasonal allergies, intranasal corticosteroids like fluticasone (Flonase) or triamcinolone (Nasacort) are the most effective over-the-counter options, providing significant relief of symptoms when used consistently for several days 1.
Key Points to Consider
- Intranasal corticosteroids are the most effective medication class in controlling symptoms of allergic rhinitis, including sneezing, itching, rhinorrhea, and nasal congestion 1.
- They work by reducing inflammation in nasal passages and can be used on a regular basis or as needed, although continuous use is generally more effective 1.
- Second-generation antihistamines like cetirizine (Zyrtec), loratadine (Claritin), or fexofenadine (Allegra) can also provide 24-hour relief with minimal drowsiness, but are generally considered less effective than intranasal corticosteroids for controlling all symptoms of allergic rhinitis 1.
- For best results, start taking these medications before allergy season begins and continue throughout the season.
- If symptoms persist after 2-3 weeks of consistent use, consider consulting a healthcare provider for prescription options.
Additional Considerations
- Nasal cromolyn sodium and leukotriene receptor antagonists (LTRAs) are less effective than intranasal corticosteroids, but may be considered for patients who are unresponsive to or noncompliant with intranasal corticosteroids 1.
- Combination therapy using an antihistamine in combination with an anti-LT or a decongestant may provide a viable alternative for patients who do not respond to intranasal corticosteroids alone 1.
- It is essential to follow the recommended dosage and administration instructions for any medication to minimize potential side effects and maximize efficacy.
From the FDA Drug Label
Fluticasone Propionate Nasal Spray, USP is an effective, allergy medicine that you can buy without a prescription. It works directly in the nose to help block your allergic reactions. Fluticasone Propionate Nasal Spray, USP relieves allergy symptoms caused by pollen, mold, dust and pets. The best over-the-counter medication for seasonal allergies is Fluticasone Propionate Nasal Spray, USP 2, as it works directly in the nose to help block allergic reactions and relieve symptoms caused by pollen, mold, dust, and pets.
- It is effective in relieving a broad range of symptoms, including sneezing, itchy nose, runny nose, itchy, watery eyes, and nasal congestion.
- It is recommended to use Fluticasone Propionate Nasal Spray, USP regularly, once a day, as it may take several days to reach maximum effect.
From the Research
Over-the-Counter Medications for Seasonal Allergies
- The study 3 found that once-daily fixed-combination loratadine/pseudoephedrine sulfate is effective in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Another study 4 compared the safety and efficacy of cetirizine plus pseudoephedrine with loratadine plus pseudoephedrine in the treatment of perennial allergic rhinitis, and found that both combinations are efficacious, with cetirizine plus pseudoephedrine providing marginally better relief of sneezing and nasal congestion.
- A recent article 5 discusses the benefits and risks of over-the-counter medications for seasonal allergies, highlighting the importance of nurses being aware of the different treatment options and lifestyle modifications to help patients manage their symptoms.
Effective Medications
- Loratadine/pseudoephedrine sulfate: effective in relieving nasal congestion in patients with seasonal allergic rhinitis 3.
- Cetirizine plus pseudoephedrine: provides marginally better relief of sneezing and nasal congestion compared to loratadine plus pseudoephedrine 4.
- Loratadine plus pseudoephedrine: also efficacious in treating perennial allergic rhinitis, although may have more treatment-related adverse events compared to cetirizine plus pseudoephedrine 4.