What is the recommended technique for administering Juvelook (hyaluronic acid) skin‑boosters to the entire face of an adult patient without active infection, uncontrolled bleeding disorders, pregnancy, or hyaluronic‑acid hypersensitivity?

Recommended Injection Technique for Juvelook Skin Boosters to the Whole Face

Juvelook should be injected using a multi-point serial puncture technique (also called nappage or microinjection technique) with small aliquots of 0.01-0.05 mL placed intradermally or in the superficial subcutaneous layer across the entire face in a grid pattern, using either a 30-31 gauge needle at 90 degrees or a blunt-tip cannula for larger areas. 1, 2

Preparation and Patient Positioning

• Cleanse the entire face using an antibacterial soap or 70% alcohol in a circular rubbing motion for at least 1 minute immediately prior to injection 3
• Position the patient supine or semi-reclined with adequate lighting to visualize injection sites 1
• Mark injection points in a grid pattern across treatment areas, spacing points approximately 0.5-1 cm apart depending on the degree of skin laxity and treatment goals 1, 2

Needle Selection and Angle

• Use a 30-31 gauge needle for precise intradermal placement, as smaller gauge needles reduce injection pain, bleeding, and bruising while allowing more accurate product delivery 4
• Inject at a 90-degree angle to the skin surface for intradermal placement, or at a 25-45 degree angle if targeting the superficial subcutaneous layer 3, 1
• For larger treatment areas (cheeks, forehead), consider switching to a blunt-tip cannula after creating entry points with a needle to minimize trauma and bruising 2

Injection Technique: Serial Puncture (Nappage)

• Pull the skin taut in the opposite direction of needle insertion to compress nerve endings and facilitate smoother skin penetration 3
• Insert the needle to the appropriate depth (intradermal or superficial subcutaneous) and inject 0.01-0.05 mL per point 1, 2
• Withdraw the needle completely before moving to the next injection point—do not thread or fan the product 3, 1
• Work systematically across the face in rows to ensure even distribution and avoid missing areas 1
• Avoid injecting into areas with active inflammation or visible blood vessels 3

Anatomical Considerations by Region

Forehead and Temples

• Use intradermal placement with 0.01-0.02 mL per point due to thinner skin 2
• Space injection points 0.5-1 cm apart in a grid pattern 1

Cheeks and Midface

• Layer the product by placing some aliquots in the deep subcutaneous layer and others more superficially for natural movement 2
• Larger volumes (0.03-0.05 mL per point) can be used in areas with more subcutaneous tissue 2
• Consider cannula technique for the medial cheek to avoid vascular complications 2

Perioral and Periorbital Areas

• Use the smallest volumes (0.01-0.02 mL) and most superficial placement due to thin skin and high vascularity 1, 2
• Increase spacing between injection points to 0.5 cm to avoid overcorrection 1

Critical Pitfalls to Avoid

• Never inject into inflamed or infected skin, as this increases the risk of complications and product-related reactions 3, 5
• Do not massage or manipulate the treated areas aggressively immediately after injection, as skin boosters are designed to integrate gradually 2
• Avoid intramuscular injection by ensuring proper depth control—skin boosters must remain in the dermis or superficial subcutaneous tissue 3, 1
• Do not use threading or fanning techniques for skin boosters, as these are designed for volumizing fillers placed in deeper planes; skin boosters require serial puncture for even distribution 1, 2

Post-Injection Care

• Inspect for air bubbles or bleeding at injection sites and apply gentle pressure if needed 3
• Advise patients to avoid makeup, excessive sun exposure, and strenuous exercise for 24 hours 3
• Monitor for delayed inflammatory reactions (erythema, swelling, tenderness) that may occur days to weeks after injection, particularly following viral illness 5, 6

Volume and Treatment Intervals

• Total volume per treatment session typically ranges from 1-3 mL for full-face treatment, depending on skin quality and patient goals 1, 2
• Repeat treatments are usually performed at 2-4 week intervals for an initial series of 2-3 sessions 2