What is the standard volume of a commercially available bottle of Ofloxacin ophthalmic solution (0.3 % w/v)?

Standard Volume for Ofloxacin Ophthalmic Solution 0.3%

Ofloxacin 0.3% ophthalmic solution is commercially available in 5 mL and 10 mL bottles. 1

Available Package Sizes

According to FDA labeling, ofloxacin ophthalmic solution 0.3% is supplied in the following standard volumes:

• 5 mL bottle (NDC 70512-793-05) 1
• 10 mL bottle (NDC 70512-793-10) 1

Both formulations are supplied sterile in opaque white LDPE plastic bottles with white dropper tips and tan high-density polyethylene (HDPE) caps. 1

Storage Requirements

The product should be stored at 20° to 25°C (68° to 77°F), with excursions permitted to 15° to 30°C (59° to 86°F), and must be protected from light. 1

Clinical Context

These bottle sizes are designed to provide adequate medication for standard treatment courses:

• For bacterial conjunctivitis: The typical 5-7 day regimen uses 1-2 drops every 2-4 hours initially, then 4 times daily 2, making the 5 mL bottle sufficient for most cases
• For bacterial keratitis: More intensive dosing (every 5-15 minutes initially, then hourly) 3 may require the larger 10 mL bottle to complete the treatment course

The 5 mL bottle is the most commonly dispensed size for routine bacterial conjunctivitis, while the 10 mL bottle may be preferred for severe infections requiring prolonged or intensive therapy. 1