What should I do about a persistent non‑healing scab on the dorsal surface of my finger for two months in an otherwise healthy adult with up‑to‑date tetanus‑diphtheria (Td) immunization and no diabetes or obvious infection?

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Persistent Non-Healing Scab on Finger: Evaluation and Management

A non-healing scab on the dorsal finger persisting for 2 months in an otherwise healthy adult warrants biopsy to exclude squamous cell carcinoma or other malignancy, as any wound lasting longer than 4 weeks should raise suspicion for underlying pathology. 1

Immediate Clinical Assessment

Key features that indicate malignancy:

  • Non-healing wound lasting >4 weeks (your case is at 8 weeks) 1
  • Rapidly growing or heaped-up appearance resembling exuberant granulation tissue 1
  • Deep, punched-out ulcer with raised or rolled edges 1
  • Hyperkeratosis surrounded by raised skin 1
  • Altered sensation (tingling or increased pain) relative to normal wounds 1

Diagnostic Approach

Obtain tissue diagnosis early through biopsy to evaluate for histological and microbiological causes, as this is essential when skin lesions fail to respond to standard wound care. 1 The differential diagnosis for a persistent finger lesion includes:

  • Squamous cell carcinoma – particularly concerning given the 2-month duration and dorsal hand location (sun-exposed area) 1
  • Actinic keratosis – precancerous lesion on sun-exposed dorsal hand 1
  • Herpetic whitlow – can present with persistent vesicles/crusting on fingers, though typically more acute 2
  • Atypical infection in immunocompromised hosts (fungal, mycobacterial) 1, 3
  • Vascular insufficiency – though less likely without systemic disease 4

When to Refer to Dermatology

Refer urgently (2-week cancer pathway) if the lesion demonstrates: 1

  • Bleeding 1
  • Pain 1
  • Thickened substance when held between finger and thumb 1
  • Failure to respond to 4 weeks of standard wound care 1

Your case meets criteria for urgent referral given the 2-month duration without healing.

Management Algorithm

Step 1: Immediate referral to dermatology for biopsy via the urgent cancer pathway, as lesions concerning for SCC require specialist evaluation within 2 weeks. 1

Step 2: Biopsy technique should include both histological assessment and microbial cultures (bacterial, fungal, viral) to identify infectious etiologies. 1

Step 3: Avoid destructive treatment (cryotherapy, curettage) until tissue diagnosis is obtained, as this may compromise diagnostic accuracy and delay appropriate cancer treatment. 1

Tetanus Status

Your tetanus immunization is adequate – no booster is needed for this wound since you are up-to-date with Td vaccination. For clean wounds in patients with ≥3 previous doses, a booster is only indicated if ≥10 years have elapsed since the last dose. 5 Even if this were classified as a contaminated wound, a booster would only be needed if ≥5 years had passed. 5

Critical Clinical Pearls

Do not assume this is simply a "slow-healing wound" – any lesion on sun-exposed skin (dorsal hand) that fails to heal within 4 weeks requires tissue diagnosis to exclude malignancy. 1 The dorsal hand is a common site for both actinic keratosis and squamous cell carcinoma due to cumulative UV exposure. 1

Avoid empiric antibiotic treatment without tissue diagnosis, as this may mask underlying pathology and delay appropriate cancer treatment. 1 Proper wound cleaning is important, but antibiotics are not indicated for tetanus prevention. 5

Document the lesion with photography and precise anatomic location before biopsy to enable monitoring of treatment response or disease evolution. 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

A man with an infected finger: a case report.

Journal of medical case reports, 2015

Research

Hand Infections in the Immunocompromised Patient: An Update.

The Journal of hand surgery, 2019

Guideline

Tetanus Vaccination for Nail Penetration Injury

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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