From the Research
For severe and multiple canker sores, topical corticosteroids are the most appropriate first-line treatment, as they directly target the inflammation and have minimal side effects, according to the most recent and highest quality study 1. When considering treatment options, it's essential to prioritize reducing pain, promoting healing, and preventing recurrence.
- Topical corticosteroids, such as triamcinolone dental paste or dexamethasone elixir rinse, are effective in managing oral aphthous ulcers, as they reduce inflammation and promote healing 2.
- Antibiotics, such as tetracycline or doxycycline, may be considered in some cases, but their use should be judicious, as canker sores are not primarily bacterial infections, but rather inflammatory lesions 3.
- Maintaining good oral hygiene and avoiding irritating foods during treatment are also crucial in supporting healing and preventing recurrence.
- Systemic medications, including antibiotics like penicillin or amoxicillin, may be necessary in severe cases, but their use should be determined by a healthcare professional on a case-by-case basis 3. It's worth noting that the pathogenesis of aphthous ulcers is not completely understood, but it is believed to involve a combination of genetic predisposition, local trauma, stress, hormonal changes, and certain environmental factors 1. Therefore, a comprehensive treatment approach that addresses the underlying causes and promotes healing is essential in managing severe and multiple canker sores.