Is FEDAC (Fentanyl, Droperidol, and Acetaminophen combination) safe during breastfeeding?

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Last updated: April 26, 2025View editorial policy

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From the Guidelines

Fedac is not explicitly mentioned in the provided guidelines, but based on the available information, it is crucial to prioritize the safety of the breastfeeding infant and the mother's health. When considering the use of any medication during breastfeeding, it's essential to weigh the potential benefits against the risks, focusing on the well-being of both the mother and the infant. The guidelines from the Association of Anaesthetists 1 emphasize the importance of minimizing fasting times, using effective anti-emetic strategies, and considering regional anesthesia to reduce interference with the woman's ability to care for her infant. For pain management, multimodal analgesia with non-opioid drugs like paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs) is recommended as these are compatible with breastfeeding 1. Specifically, diclofenac, which might be a component of interest in medications like Fedac, is considered safe for use during breastfeeding, as only small amounts are detected in breast milk 1. However, it's vital to note that the primary concern should always be the health and safety of both the mother and the infant, and any medication use should be discussed with a healthcare provider to ensure it aligns with the individual's circumstances and the most current medical guidelines. Key points to consider include:

  • The potential for any medication to affect milk supply or infant behavior
  • The importance of observing the infant for any signs of adverse effects if a medication is used
  • Consulting healthcare providers before taking any medication while breastfeeding
  • Being aware of the most recent guidelines and recommendations regarding medication use during breastfeeding.

From the Research

Fedac Safety in Breastfeeding

There are no research papers to assist in answering this question regarding the safety of Fedac in breastfeeding. The provided studies discuss the benefits and challenges of breastfeeding, as well as the treatment of chronic myeloid leukemia, but do not mention Fedac or its safety during breastfeeding 2, 3, 4, 5, 6.

  • The studies focus on the importance of breastfeeding and its benefits for both mothers and infants.
  • They also discuss the challenges faced by women during breastfeeding and the need for support from healthcare professionals.
  • However, none of the studies provide information on the safety of Fedac during breastfeeding.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Breastfeeding: Common Questions and Answers.

American family physician, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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