From the Guidelines
I'm unable to provide a meaningful answer to "Psuduçàlf hypert" as it appears to be a nonsensical term or phrase that doesn't correspond to any recognized medical condition, medication, or scientific concept in English or other languages. The combination of letters doesn't form a recognizable word in medical terminology, and "hypert" could potentially be referring to hypertension, but the preceding term has no clear meaning. Without a clear, legitimate question about a medical condition or treatment, I cannot provide specific recommendations, medication names, dosages, or scientific reasoning. If you have a specific medical question, please rephrase it using standard medical terminology so I can provide an appropriate response, based on the most recent and highest quality studies, such as the 2021 guideline-driven management of hypertension update 1. Some key points from this study include the importance of accurate diagnosis and treatment of hypertension to reduce the risk of cardiovascular disease and all-cause mortality, as well as the need for lifestyle modification and pharmacological treatment to achieve optimal blood pressure control. However, these points are not directly applicable to the question at hand, as the term "Psuduçàlf hypert" is not a recognized medical condition. Therefore, I must reiterate that a clear and legitimate question is necessary to provide a meaningful answer, and I encourage you to rephrase your question using standard medical terminology.
From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Hypertension Overview
- Hypertension is defined as persistent systolic blood pressure (SBP) at least 130 mm Hg or diastolic BP (DBP) at least 80 mm Hg 2
- It affects approximately 116 million adults in the US and more than 1 billion adults worldwide, and is associated with increased risk of cardiovascular disease (CVD) events and death 2
Treatment of Hypertension
- First-line therapy for hypertension is lifestyle modification, including weight loss, healthy dietary pattern, physical activity, and moderation or elimination of alcohol consumption 2
- First-line drug therapy for hypertension consists of a thiazide or thiazidelike diuretic, an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, and a calcium channel blocker 2, 3
- The decision to initiate antihypertensive medication should be based on the level of BP and the presence of high atherosclerotic CVD risk 2
Angiotensin-Converting Enzyme Inhibitors
- Angiotensin-converting enzyme (ACE) inhibitors are a type of antihypertensive medication that target the renin-angiotensin system (RAS) 4, 5
- ACE inhibitors have been shown to be effective in reducing blood pressure and cardiovascular risk, but may be associated with side effects such as cough and angioedema 4
- Angiotensin receptor blockers (ARBs) are an alternative to ACE inhibitors and have been shown to have similar efficacy with fewer side effects 4
Combination Therapy
- Combination antihypertensive therapy, such as a fixed-dose ACE inhibitor-diuretic combination, may be effective in reducing ambulatory blood pressures and arterial stiffness in isolated systolic hypertension 6
- Combination therapy may be useful in achieving blood pressure control and reducing cardiovascular risk, particularly in patients with resistant or difficult-to-treat hypertension 3, 6