Can Manuka (Leptinella) eye drops alter iris pigmentation?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 26, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

No, Manuka eye drops are not known to lighten iris color. These drops, derived from Manuka honey, are sometimes used for their antibacterial and anti-inflammatory properties to treat dry eyes or mild eye infections, but they have no effect on melanin production or distribution in the iris. Iris color is primarily determined by genetics and the amount of melanin in the iris stroma. The only medications known to potentially change iris color are prostaglandin analogs like bimatoprost (Latisse) or latanoprost (Xalatan), which are used for glaucoma treatment or eyelash growth and can sometimes darken light-colored irises as a side effect by increasing melanin production. This effect is typically permanent and occurs gradually over months of regular use.

Key Points to Consider

  • Manuka eye drops have been studied for their efficacy in treating dry eye, with some studies showing significant improvements in symptoms and tear quality 1, 2.
  • However, there is no evidence to suggest that Manuka eye drops can change iris color, as this is determined by genetics and melanin production in the iris stroma.
  • Other methods for changing eye color, such as cosmetic iris implants or laser treatments, have been associated with significant risks and complications, including vision loss and eye damage 3, 4.
  • If you're interested in changing your eye color, be aware that there are no safe, effective, and FDA-approved methods to do so cosmetically, and attempting to do so with unproven products could potentially damage your eyes.

Important Considerations for Eye Health

  • Any attempts to change eye color should be approached with caution and under the guidance of a qualified eye care professional.
  • The use of unproven or unapproved products for changing eye color can result in serious complications, including vision loss and eye damage.
  • Prioritizing eye health and safety is essential when considering any cosmetic or therapeutic procedures for the eyes.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.