From the FDA Drug Label
One or two capsules every four hours. Total daily dosage should not exceed 6 capsules. The recommended dose of Fioricet is one or two capsules and the recommended frequency is every four hours, with a maximum daily dose of 6 capsules 1.
From the Research
Fioricet should be taken in a dose of 1-2 tablets every 4 hours as needed, with a maximum of 6 tablets in 24 hours, due to the risk of dependence from the butalbital component and potential for medication overuse headache 2, 3. The medication contains acetaminophen, butalbital (a barbiturate), and caffeine, and is typically prescribed for tension headaches.
Important Considerations
- Treatment should be limited to short durations to minimize the risk of dependence from the butalbital component 2.
- Patients should be aware of potential side effects including drowsiness, dizziness, and stomach upset.
- It's essential not to exceed the recommended acetaminophen daily limit (3,000-4,000 mg) to avoid liver damage.
- Alcohol should be avoided while taking this medication as it increases sedation risks.
- A study from 2017 found that caffeine doses of 130 mg can enhance the efficacy of analgesics in tension-type headaches, which is relevant to Fioricet's formulation 4.
Clinical Guidance
If you're experiencing headaches requiring medication, please consult with your healthcare provider for proper diagnosis and personalized dosing instructions based on your specific condition and medical history.
Key Points to Discuss with Your Healthcare Provider
- Your medical history and current health status
- The severity and frequency of your headaches
- Any previous treatments or medications you've used for headaches
- Potential interactions with other medications you're taking
- Strategies for minimizing the risk of medication overuse headache and dependence on butalbital 3.