What are the causes of non-standard vulvar bumps?

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Last updated: April 26, 2025View editorial policy

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Differential Diagnosis for Non-STD Vulvar Bumps

Single Most Likely Diagnosis

  • Vulvar cysts or Bartholin's cysts: These are common, benign conditions that can cause bumps on the vulva. They often result from obstructed Bartholin's glands and can become infected, leading to abscess formation.

Other Likely Diagnoses

  • Folliculitis: An inflammation of the hair follicles, which can be caused by bacterial or fungal infections, leading to bumps on the vulva.
  • Keratosis pilaris: A harmless condition that causes small, rough bumps on the skin, including the vulva, due to excess keratin.
  • Vulvar acne: Similar to acne on other parts of the body, vulvar acne can cause bumps and pimples due to clogged pores and bacterial infection.
  • Molluscum contagiosum: A viral infection that causes small, pearly, or flesh-colored bumps on the skin, including the vulva.

Do Not Miss Diagnoses

  • Squamous cell carcinoma: A type of skin cancer that can present as a bump or ulcer on the vulva. Early detection is crucial for effective treatment.
  • Melanoma: Although rare on the vulva, melanoma can present as a new or changing mole and is potentially life-threatening if not diagnosed early.
  • Vulvar intraepithelial neoplasia (VIN): Precancerous changes in the skin of the vulva that can appear as bumps or lesions and have the potential to develop into cancer if left untreated.

Rare Diagnoses

  • Hidradenitis suppurativa: A chronic skin condition that can cause painful bumps and abscesses in the vulvar area, among other places.
  • Vulvar syringoma: A rare, benign condition characterized by small, firm bumps on the vulva due to abnormal sweat gland development.
  • Neurofibromas: Benign tumors of the nerve tissue that can appear as bumps on the vulva in individuals with neurofibromatosis type 1 (NF1).

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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