How to treat a cat with arterial thrombosis (blood clot) in a limb?

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Last updated: April 26, 2025View editorial policy

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From the FDA Drug Label

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From the Research

A cat with a thrombosis in the paw requires immediate veterinary care, and the standard treatment involves hospitalization, pain management, and anti-platelet drugs such as clopidogrel (Plavix) at 18.75 mg once daily for cats, as supported by the most recent and highest quality study 1. The treatment of thrombosis in cats is a complex and potentially life-threatening condition that cannot be treated at home.

  • The condition occurs when blood clots form, often due to underlying heart disease, and block blood flow to the limb, causing pain, paralysis, and cold extremities.
  • The prognosis varies depending on how quickly treatment begins and the extent of the clot, but many cats require long-term medication to prevent recurrence.
  • According to the study 1, clopidogrel administration in cats at risk of arterial thrombosis is supported by the literature, and specific protocols were recommended.
  • Another study 2 suggests that thrombolytics may be considered in certain cases, but substantial additional research is needed to address the role of thrombolytics for the treatment of arterial and venous thrombosis in cats.
  • It is essential to follow the veterinarian's instructions precisely regarding medication administration and follow-up care, as human medications can be toxic to cats.
  • The use of anticoagulants, such as low molecular weight heparin, may also be recommended, as well as vasodilators to improve blood flow.
  • During recovery, the cat will need strict cage rest, gentle physical therapy, and careful monitoring of the affected limb.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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